NCS1 and NBL1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NCS1	NBL1
Description		neuronal calcium sensor 1	NBL1, DAN family BMP antagonist
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Plasma Membrane Postsynaptic Density Cell Junction Dendrite Dense Core Granule Intracellular Membrane-bounded Organelle Calyx Of Held Perinuclear Region Of Cytoplasm Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol	Extracellular Space
	Molecular Function	Magnesium Ion Binding Voltage-gated Calcium Channel Activity Calcium Ion Binding Protein Binding Protein Kinase Binding Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels	Protein Binding Morphogen Activity BMP Binding Identical Protein Binding
	Biological Process	Regulation Of Neuron Projection Development Positive Regulation Of Exocytosis Phosphatidylinositol-mediated Signaling Calcium Ion Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Synaptic Vesicle Exocytosis	Signal Transduction Nervous System Development Negative Regulation Of BMP Signaling Pathway Sequestering Of BMP In Extracellular Matrix Sequestering Of BMP From Receptor Via BMP Binding Positive Regulation Of Neuron Differentiation Determination Of Dorsal Identity Neuron Projection Morphogenesis Negative Regulation Of Monocyte Chemotaxis
Pathways
Drugs		Calcium Citrate Calcium Phosphate
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Tuberculosis ( 30713548)	Blood protein levels ( 30072576) Bronchopulmonary dysplasia in preterm infants ( 30113228) Serum thyroid-stimulating hormone levels ( 24852370)
Interacting Genes		10 interacting genes: DRD2 DRD3 DRD5 DTX2 EXOSC2 GRK2 IL1RAPL1 KCND2 NBL1 PI4KB	4 interacting genes: BAG6 NCS1 UBQLN1 ZMIZ2
Entrez ID		23413	4681
HPRD ID		04500	09001
Ensembl ID		ENSG00000107130	ENSG00000158747
Uniprot IDs		A0A024R8B2 P62166	A0A087WTY6 P41271
PDB IDs		1G8I 2LCP 4GUK 5O9S 6QI4	4X1J 4YU8
Enriched GO Terms of Interacting Partners?
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