SIK3 and CRTC2

Number of citations of the paper that reports this interaction (PubMedID 16306228)
45

Data Source:
HPRD (in vivo, in vitro)

		SIK3	CRTC2
Description		SIK family kinase 3	CREB regulated transcription coactivator 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Tau-protein Kinase Activity	Chromatin Binding Protein Binding CAMP Response Element Binding Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Protein Phosphorylation Intracellular Signal Transduction Positive Regulation Of TORC1 Signaling Positive Regulation Of TORC2 Signaling	Gluconeogenesis Viral Process Positive Regulation Of CREB Transcription Factor Activity Glucose Homeostasis Histone H3-K9 Acetylation Positive Regulation Of Transcription By RNA Polymerase II Protein Homotetramerization Toxin Transport
Pathways			Transcriptional activation of mitochondrial biogenesis Circadian Clock
Drugs
Diseases
GWAS		Allergic rhinitis ( 30013184) Blood protein levels ( 28240269) Delirium ( 29631748) Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) HDL cholesterol ( 31170924 24886709) Hearing function ( 25060954) Medication use (thyroid preparations) ( 31015401) Metabolic syndrome ( 30382898) Non-accommodative esotropia ( 30098192) Response to Vitamin E supplementation ( 22437554) Sum eosinophil basophil counts ( 27863252) Triglyceride levels ( 29615537) Triglycerides ( 24886709)	Age at first birth ( 27798627) Empathy quotient ( 29527006)
Interacting Genes		7 interacting genes: ATP5MG CRTC2 HDAC5 PRKACA TRAF1 TRIP6 YWHAZ	9 interacting genes: MFHAS1 PPP3CA PRKAA1 SIK1 SIK2 SIK3 YWHAB YWHAG YWHAZ
Entrez ID		23387	200186
HPRD ID		11121	12347
Ensembl ID		ENSG00000160584	ENSG00000160741
Uniprot IDs		A1A5A9 Q9Y2K2	Q53ET0
PDB IDs			4HTM
Enriched GO Terms of Interacting Partners?
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