ARHGEF12 and RHOA

  • Number of citations of the paper that reports this interaction (PubMedID 11373293)
  • 38
  • Data Source:
  • HPRD (in vivo, in vitro)

ARHGEF12

RHOA

Description Rho guanine nucleotide exchange factor 12 ras homolog family member A
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 28240269)
  • Cognitive function ( 25644384)
  • Coronary artery disease ( 29212778 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Crohn's disease ( 28067908)
  • Extremely high intelligence ( 29520040)
  • General cognitive ability ( 29844566)
  • Gut microbiota (functional units) ( 27694959)
  • Household income (MTAG) ( 31844048)
  • Inflammatory bowel disease ( 28067908)
  • Mood instability ( 31168069)
  • Morning person ( 30696823)
  • Regular attendance at a religious group ( 29970889)
  • Sleep duration (short sleep) ( 30846698)
  • Ulcerative colitis ( 28067908)
Interacting Genes 18 interacting genes: ABCA1 CD44 CLK1 CUL3 EGFR GIPC1 GNA12 GNA13 IGF1R KLHL20 LPAR1 LPAR2 PLXNB1 PLXNB2 PTPRF RHOA RPS6KA1 TEC 109 interacting genes: ACKR2 AGAP1 AGAP2 AKAP13 AMT ARF4 ARHGAP1 ARHGAP10 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP5 ARHGAP8 ARHGDIA ARHGDIB ARHGDIG ARHGEF1 ARHGEF11 ARHGEF12 ARHGEF18 ARHGEF2 ARHGEF25 ARHGEF28 ARHGEF3 ARHGEF4 ARIH2 ARNTL BCR BIRC2 C1QA CAMP CAV1 CIT CLOCK CNKSR1 CNTNAP1 DAAM1 DCUN1D1 DEF6 DGKQ DIAPH1 DIAPH3 DOCK7 DVL2 ENTPD3 FLNA FMN2 GMIP GPX1 HSPA1A ICMT IKBKG IKZF3 ITIH3 ITPR1 KCNA2 KCTD13 KLRG1 KTN1 LRP2 MCF2 MCF2L MPRIP NET1 NOTCH1 OPHN1 OTUB1 PDCD10 PDE6D PITPNM1 PKN1 PKN2 PLCG1 PLD1 PLEKHG2 PPP1R12A PRKACA PRKCA PRKCZ PTPRF RABAC1 RACK1 RAP1GDS1 RASGRF1 RASSF1 RHPN1 RHPN2 RIPK4 RIPOR2 ROCK1 RPN2 RTKN SH3BP1 SMAD2 SMURF1 SMURF2 SPRED2 SRGAP1 SUB1 TGFBR1 TGM2 TNFAIP1 TRIO TRIP6 TRPC1 VAV1 VAV2 VAV3
Entrez ID 23365 387
HPRD ID 09207 01323
Ensembl ID ENSG00000196914 ENSG00000067560
Uniprot IDs B4E2K6 E9PMR6 Q9NZN5 A0A024R324 B4DKN9 C9JRM1 C9JX21 P61586 Q9BVT0
PDB IDs 1TXD 1X86 2OMJ 2OS6 1A2B 1CC0 1CXZ 1DPF 1FTN 1KMQ 1LB1 1OW3 1S1C 1TX4 1X86 1XCG 2RGN 3KZ1 3LW8 3LWN 3LXR 3MSX 3T06 4D0N 4XH9 4XOI 4XSG 4XSH 5A0F 5BWM 5C2K 5C4M 5EZ6 5FR1 5FR2 5HPY 5IRC 5JCP 5JHG 5JHH 5M6X 5M70 5ZHX 6BC0 6BCA 6BCB 6R3V
Enriched GO Terms of Interacting Partners?
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