ICOSLG and SLC27A2

		ICOSLG	SLC27A2
Description		inducible T cell costimulator ligand	solute carrier family 27 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome	Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Protein Binding Identical Protein Binding	Acyl-CoA Ligase Activity Long-chain Fatty Acid-CoA Ligase Activity Long-chain Fatty Acid Transporter Activity ATP Binding Fatty Acid Transmembrane Transporter Activity Enzyme Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity Cholate-CoA Ligase Activity Phytanate-CoA Ligase Activity Pristanate-CoA Ligase Activity Decanoate-CoA Ligase Activity
	Biological Process	Regulation Of Cytokine Production Adaptive Immune Response Defense Response Hyperosmotic Response Signal Transduction T Cell Costimulation Positive Regulation Of Activated T Cell Proliferation T Cell Activation B Cell Activation Regulation Of Immune Response T Cell Receptor Signaling Pathway	Fatty Acid Alpha-oxidation Long-chain Fatty Acid Metabolic Process Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Very Long-chain Fatty Acid Catabolic Process Neutrophil Degranulation Long-chain Fatty Acid Import Methyl-branched Fatty Acid Metabolic Process
Pathways		Costimulation by the CD28 family	Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol Alpha-oxidation of phytanate Neutrophil degranulation Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Blood protein levels ( 30072576 29875488) Celiac disease ( 22057235 20190752) Cerebral amyloid deposition (PET imaging) ( 30361487) Crohn's disease ( 18587394 21102463) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Inflammatory bowel disease ( 23128233) Left ventricular QRS voltage ( 27195777) Rheumatoid arthritis ( 30423114) Type 1 diabetes ( 25751624) Ulcerative colitis ( 21297633)	Blood metabolite ratios ( 24816252) Verbal declarative memory ( 25648963)
Interacting Genes		2 interacting genes: ICOS SLC27A2	17 interacting genes: ABCD1 AP4E1 ARPP19 DTWD1 FAM214A GABPB1 GEMIN5 ICOSLG LGI1 PDCD11 PDE6G PEX5 PML RAB5C SLC24A1 UBC YWHAQ
Entrez ID		23308	11001
HPRD ID		05757	11935
Ensembl ID		ENSG00000160223	ENSG00000140284
Uniprot IDs		A0N0L8 B7Z1W8 O75144	O14975
PDB IDs
Enriched GO Terms of Interacting Partners?
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