ARL6IP1 and WIPI2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ARL6IP1	WIPI2
Description		ADP ribosylation factor like GTPase 6 interacting protein 1	WD repeat domain, phosphoinositide interacting 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Phagophore Assembly Site Nucleoplasm Autophagosome Cytosol Membrane Extrinsic Component Of Membrane Protein-containing Complex Phagophore Assembly Site Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation Cellular Response To Starvation Macroautophagy Protein Localization To Phagophore Assembly Site Autophagy Of Nucleus Protein Lipidation Involved In Autophagosome Assembly Autophagosome Maturation Xenophagy
Pathways			Macroautophagy
Drugs
Diseases
GWAS			Bone mineral density x blood lead interaction in current smokers (1df test) ( 29518117) Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252)
Interacting Genes		41 interacting genes: ACSF2 ARL4D ARL6 CERT1 DIABLO FBXW7 FDFT1 FXR2 GAD2 GOLPH3 GOLPH3L GORASP2 HGS HMGCL INPP5K LMNA MTERF3 MYG1 NAPB NDRG4 NUDT3 PAM16 PBX3 RAB33A RETREG3 SENP2 SHMT2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX3 SNX4 SPG21 SUCLA2 TFAM TUFM WIPI2 ZFYVE21 ZNF391	11 interacting genes: ARL6IP1 COPS6 DDB1 MTOR OPTN POT1 RABAC1 RPTOR STRN4 TERF2IP UBE2L3
Entrez ID		23204	26100
HPRD ID		09641	15679
Ensembl ID		ENSG00000170540	ENSG00000157954
Uniprot IDs		A0A024QYV7 Q15041	A0A024R823 Q9Y4P8
PDB IDs
Enriched GO Terms of Interacting Partners?
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