MPRIP and RACGAP1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		MPRIP	RACGAP1
Description		myosin phosphatase Rho interacting protein	Rac GTPase activating protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Focal Adhesion Actin Cytoskeleton	Acrosomal Vesicle Nucleus Nucleoplasm Cytosol Microtubule Midbody Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cleavage Furrow Spindle Midzone Extracellular Exosome Mitotic Spindle Flemming Body Centralspindlin Complex
	Molecular Function	Actin Binding Protein Binding Cadherin Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Microtubule Binding Protein Kinase Binding Alpha-tubulin Binding Gamma-tubulin Binding Metal Ion Binding Beta-tubulin Binding
	Biological Process		Mitotic Cytokinesis Actomyosin Contractile Ring Assembly Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Spermatogenesis Neuroblast Proliferation Sulfate Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Cytokinesis Intracellular Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Embryonic Development Regulation Of Small GTPase Mediated Signal Transduction Mitotic Spindle Midzone Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Pathways		Signaling by BRAF and RAF fusions	Rho GTPase cycle MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Diabetic retinopathy ( 21441570) Estimated glomerular filtration rate ( 31152163) Obesity-related traits ( 23251661)
Interacting Genes		15 interacting genes: ATXN7 COL6A1 IKBKG LSM8 NOS3 PIAS4 PPP1R12A PPP1R12C PTEN RACGAP1 RHOA YTHDC1 YWHAB YWHAG YWHAQ	28 interacting genes: AURKB CDK1 CHN2 ECT2 HIF1A KIF23 MAP3K10 MAP3K4 MORF4L1 MPRIP NRAS PLK1 PPP2CA PPP2R5E PRC1 PRSS23 PTPA RND2 SH3RF1 SLC16A10 SLC26A8 TANK TUBA4A TUBG1 TXNDC11 VAV1 YWHAB YWHAG
Entrez ID		23164	29127
HPRD ID		17591	05402
Ensembl ID		ENSG00000133030	ENSG00000161800
Uniprot IDs		Q6WCQ1 Q8N236	A0A024R136 B2RE34 Q9H0H5
PDB IDs			2OVJ 3W6R 3WPQ 3WPS 4B6D 5C2J 5C2K
Enriched GO Terms of Interacting Partners?
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