SNX13 and G6PC

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SNX13	G6PC
Description		sorting nexin 13	glucose-6-phosphatase catalytic subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Early Endosome Early Endosome Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding	Glucose-6-phosphatase Activity Phosphotransferase Activity, Alcohol Group As Acceptor Phosphate Ion Binding
	Biological Process	Intracellular Protein Transport Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity	Glycogen Metabolic Process Glycogen Catabolic Process Gluconeogenesis Triglyceride Metabolic Process Steroid Metabolic Process Response To Carbohydrate Regulation Of Gene Expression Glucose-6-phosphate Transport Response To Food Cellular Response To Insulin Stimulus Multicellular Organism Growth Glucose Homeostasis Cholesterol Homeostasis Urate Metabolic Process Phosphorylated Carbohydrate Dephosphorylation Glucose 6-phosphate Metabolic Process Response To Resveratrol
Pathways			Glycogen storage disease type Ia (G6PC) Gluconeogenesis FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Creatine kinase levels ( 29403010) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422) HDL cholesterol ( 24097068 30275531) HDL cholesterol levels ( 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Heel bone mineral density ( 30598549) Lactate dehydrogenase levels ( 29403010) LDL cholesterol levels x long total sleep time interaction (1df test) ( 31719535) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Metabolic syndrome ( 31589552) Severe influenza A (H1N1) infection ( 26379185) Tea consumption ( 31046077) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		5 interacting genes: G6PC GNAS KLF15 NR1I3 TDP2	4 interacting genes: CDH16 FOXO1 NSL1 SNX13
Entrez ID		23161	2538
HPRD ID		09418	01983
Ensembl ID		ENSG00000071189	ENSG00000131482
Uniprot IDs		A0A024R9Z9 Q86XC4 Q9Y5W8	P35575
PDB IDs
Enriched GO Terms of Interacting Partners?
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