EPB41L3 and IGSF21

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		EPB41L3	IGSF21
Description		erythrocyte membrane protein band 4.1 like 3	immunoglobin superfamily member 21
Image			No pdb structure
GO Annotations	Cellular Component	Cell Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Postsynaptic Density Cell Junction Axolemma Paranode Region Of Axon Juxtaparanode Region Of Axon	Adherens Junction Anchored Component Of External Side Of Plasma Membrane Presynaptic Membrane Postsynaptic Membrane Inhibitory Synapse
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding	Signaling Receptor Activity Protein Homodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Regulation Of Cell Growth Protein Localization To Paranode Region Of Axon Apoptotic Process Cytoskeletal Anchoring At Plasma Membrane Biological_process Regulation Of Cell Shape Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Paranodal Junction Assembly Actomyosin Structure Organization Myelin Maintenance Neuron Projection Morphogenesis Protein Localization To Juxtaparanode Region Of Axon Protein Localization To Plasma Membrane	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Synapse Maturation
Pathways		Neurexins and neuroligins
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Chronic kidney disease ( 31152163) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Glomerular filtration rate (creatinine) ( 28452372) Optic nerve head parameters (multi-trait analysis) ( 31798171) Sleep duration ( 25469926) Social communication problems ( 24564958) Thyroid nodules ( 30099483) Vertical cup-disc ratio ( 31798171)	Atypical femoral fracture in phosphonate treatment ( 31006051) Cobalt levels ( 26025379) Diabetic retinopathy ( 21441570) Erectile dysfunction and prostate cancer treatment ( 20932654) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171) Survival in pancreatic cancer ( 28470677)
Interacting Genes		18 interacting genes: ATXN1L CADM1 CEP152 CLNS1A CNTNAP2 HSPB1 IGSF21 MBIP PAXIP1 PSEN1 SPTBN1 TCF4 UNC13A YWHAB YWHAG YWHAH YWHAQ YWHAZ	32 interacting genes: ALDH2 ANXA3 ATF3 BCR BTBD2 CRCT1 DGKD EPB41L3 ERH ETHE1 GADD45A GIPC2 GSK3B GSTM4 HSPB1 KRAS MAD2L1BP NACA NREP PAEP PAFAH1B3 PCDHA4 PRMT1 PSMD11 RPP14 S100A8 SEPHS1 SERPINB9 SULT1E1 TMSB4X TRBV2 UBE2V2
Entrez ID		23136	84966
HPRD ID		05622	11309
Ensembl ID		ENSG00000082397	ENSG00000117154
Uniprot IDs		A0A0A0MRA8 A8K968 Q9Y2J2	Q96ID5
PDB IDs		2HE7 3BIN 6IBE
Enriched GO Terms of Interacting Partners?
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