EMC1 and OTUD3

		EMC1	OTUD3
Description		ER membrane protein complex subunit 1	OTU deubiquitinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Protein-containing Complex ER Membrane Protein Complex	Cytoplasm Cytosol
	Molecular Function		Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Thiol-dependent Ubiquitinyl Hydrolase Activity
	Biological Process		Protein Deubiquitination Protein K11-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Negative Regulation Of Protein Kinase B Signaling Protein K48-linked Deubiquitination Protein K27-linked Deubiquitination
Pathways			Ovarian tumor domain proteases Regulation of PTEN stability and activity
Drugs
Diseases
GWAS			group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 19915572 28067908 20228798 20228799 19122664 23511034)
Interacting Genes		8 interacting genes: AKR7A2 KEL LNPK OTUD3 PADI2 PCP4 SZRD1 TTC27	3 interacting genes: EMC1 PTEN UBC
Entrez ID		23065	23252
HPRD ID		08306	19417
Ensembl ID		ENSG00000127463	ENSG00000169914
Uniprot IDs		Q8N766	Q5T2D3
PDB IDs			4BOU
Enriched GO Terms of Interacting Partners?
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