SETX and PRRC2B

		SETX	PRRC2B
Description		senataxin	proline rich coiled-coil 2B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Body Axon Growth Cone Intercellular Bridge
	Molecular Function	Transcription Termination Site Sequence-specific DNA Binding DNA Binding DNA Helicase Activity RNA Binding Protein Binding ATP Binding Identical Protein Binding	RNA Binding Protein Binding
	Biological Process	MAPK Cascade Double-strand Break Repair DNA Recombination DNA-templated Transcription, Termination Termination Of RNA Polymerase II Transcription MRNA Splice Site Selection RNA Processing Cellular Response To DNA Damage Stimulus Spermatogenesis Circadian Rhythm Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development DNA Duplex Unwinding Positive Regulation Of RNA Splicing Cellular Response To Oxidative Stress Negative Regulation Of Apoptotic Process Protein Kinase B Signaling Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription, Termination Cellular Response To Hydrogen Peroxide Cellular Response To Retinoic Acid Positive Regulation Of DNA-templated Transcription, Initiation Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled	Cell Differentiation
Pathways
Drugs
Diseases		Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease Ataxia with ocular apraxia (AOA), including: Ataxia telangiectasia (AT); Ataxia telangiectasia like disorder (ATLD); Ataxia oculomotor apraxia type 1 (AOA1); Ataxia oculomotor apraxia type 2 (AOA2) Distal hereditary motor neuropathies (dHMN)
GWAS		Current cigarettes per day in chronic obstructive pulmonary disease ( 29631575) Metabolite levels ( 23823483)	Urate levels ( 31578528)
Interacting Genes		6 interacting genes: BRCA1 PRRC2B PTEN SUMO1 SUMO2 UBE2I	18 interacting genes: AK8 APP ATN1 ATXN1 ATXN1L CFAP77 CRK DDX31 DNAJC5 DPY30 EHMT2 FBXO7 GTF3C4 PLPP7 RERE SETX SRPK2 UCK1
Entrez ID		23064	84726
HPRD ID		07622	13805
Ensembl ID		ENSG00000107290	ENSG00000130723
Uniprot IDs		Q7Z333	Q5JSZ5 Q9BU62
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?