PALLD and SORBS2

Number of citations of the paper that reports this interaction (PubMedID 16125169)
26

Data Source:
BioGRID (two hybrid)

		PALLD	SORBS2
Description		palladin, cytoskeletal associated protein	sorbin and SH3 domain containing 2
Image
GO Annotations	Cellular Component	Stress Fiber Ruffle Podosome Nucleus Cytosol Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Z Disc Lamellipodium Axon Growth Cone Excitatory Synapse	Nucleus Plasma Membrane Focal Adhesion Actin Cytoskeleton Apical Plasma Membrane Z Disc Lamellipodium Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Protein Binding Muscle Alpha-actinin Binding Cell-cell Adhesion Mediator Activity	RNA Binding Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Adaptor Activity Structural Constituent Of Muscle
	Biological Process	Keratinocyte Development Epithelial Cell Morphogenesis Cytoskeleton Organization Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Cell Migration Actin Cytoskeleton Organization Dendrite Self-avoidance	Actin Filament Organization Notch Signaling Pathway Biological_process Cell Growth Involved In Cardiac Muscle Cell Development
Pathways
Drugs
Diseases
GWAS		Advanced glycation end-product levels ( 26915486) Bacteremia ( 27236921) Coronary artery disease ( 29212778) Non-alcoholic fatty liver disease histology (AST) ( 20708005) Pulse pressure ( 28135244 27841878 30578418) Response to iloperidone treatment (QT prolongation) ( 18521091) Systolic blood pressure ( 30578418) Vein graft stenosis in coronary artery bypass grafting ( 25881214)	Cardiac Troponin-T levels ( 31014085) Cytokine and corticosteroid-stimulated IL-6 production ( 25896417) Cytokine-stimulated IL-6 production ( 25896417) Height ( 31562340) Short-term memory (digit-span task) ( 30741946) Uterine fibroid size (maximum volume) ( 30196971) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		7 interacting genes: ACTN1 ACTN2 EZR ITGB5 LIG4 SORBS2 SRPK2	37 interacting genes: ABL1 ABL2 ACTN1 ACTN4 ADAM15 AFDN AKT1 AKT2 ATPAF2 CBL DLGAP1 DLGAP2 DLGAP4 EFS EGFR FAT1 FLOT1 MDM2 NCK2 NR1H2 PAK1 PAK2 PALLD PKM PTK2B PTPN12 RPL9 SEMA6A SH2D4A SYNJ1 TRAF4 VCL VPS37C WAS WASF1 YWHAE YWHAZ
Entrez ID		23022	8470
HPRD ID		09731	12473
Ensembl ID		ENSG00000129116	ENSG00000154556
Uniprot IDs		B2RTX2 Q8WX93	B7Z3D7 B7Z997 O94875
PDB IDs		2DM2 2DM3	5VEI
Enriched GO Terms of Interacting Partners?
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