DAAM1 and AMBP

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		DAAM1	AMBP
Description		dishevelled associated activator of morphogenesis 1	alpha-1-microglobulin/bikunin precursor
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GO Annotations	Cellular Component	Stress Fiber Cytosol Plasma Membrane Membrane Motile Cilium Ciliary Basal Body	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Actin Binding Protein Binding Rho GTPase Binding Identical Protein Binding	Serine-type Endopeptidase Inhibitor Activity Protein Binding Calcium Channel Inhibitor Activity IgA Binding Heme Binding Protein Homodimerization Activity Calcium Oxalate Binding
	Biological Process	Actin Cytoskeleton Organization Wnt Signaling Pathway, Planar Cell Polarity Pathway	Receptor-mediated Endocytosis Cell Adhesion Female Pregnancy Negative Regulation Of Endopeptidase Activity Viral Process Protein-chromophore Linkage Protein Catabolic Process Heme Catabolic Process Negative Regulation Of JNK Cascade Negative Regulation Of Immune Response
Pathways		PCP/CE pathway RHO GTPases Activate Formins	Scavenging of heme from plasma
Drugs			Human Serum Albumin
Diseases
GWAS		Inferior temporal gyrus volume ( 31530798) Occipital lobe volume ( 31396565) Optic disc size ( 31809533) Parietal lobe volume ( 31396565) Parkinsonism in frontotemporal lobe dementia ( 29724592) Type 2 diabetes ( 25483131)	Blood protein levels ( 29875488)
Interacting Genes		6 interacting genes: AMBP B3GALT4 DVL1 DVL2 PRPF40A RHOA	13 interacting genes: A2M ALB COX8A DAAM1 ENO1 EXOSC2 F2 FHL3 FN1 GRB2 PIK3CA PIK3R3 STAT3
Entrez ID		23002	259
HPRD ID		09433	01467
Ensembl ID		ENSG00000100592	ENSG00000106927
Uniprot IDs		Q9Y4D1	P02760
PDB IDs		2J1D 2Z6E	1BIK 3QKG 4ES7 4U30 6EJ7 6EJ8 6EJ9 6EJA 6EJB 6EJC 6EJD
Enriched GO Terms of Interacting Partners?
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