CEP131 and MIB1

Number of citations of the paper that reports this interaction (PubMedID 24121310)
48

Data Source:
BioGRID (affinity chromatography technology, pull down)

		CEP131	MIB1
Description		centrosomal protein 131	mindbomb E3 ubiquitin protein ligase 1
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Centrosome Cytosol Microtubule Cytoskeleton Centriolar Satellite Ciliary Transition Zone Ciliary Basal Body Intracellular Membrane-bounded Organelle Intercellular Bridge	Cytoplasm Centrosome Cytosol Plasma Membrane Postsynaptic Density Cytoplasmic Vesicle
	Molecular Function	Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Multicellular Organism Development Spermatogenesis Positive Regulation Of Cell Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Centrosome Duplication Cell Differentiation Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Protein Localization To Centrosome Positive Regulation Of Intracellular Protein Transport Ciliary Basal Body-plasma Membrane Docking	Blood Vessel Development In Utero Embryonic Development Somitogenesis Neural Tube Formation Heart Looping Ubiquitin-dependent Protein Catabolic Process Endocytosis Notch Signaling Pathway Protein Ubiquitination Negative Regulation Of Neuron Differentiation Positive Regulation Of Endocytosis
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Activated NOTCH1 Transmits Signal to the Nucleus Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants NOTCH2 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus
Drugs
Diseases
GWAS		Frontotemporal dementia ( 26154020)	Severe progression in rheumatoid arthritis ( 29065906)
Interacting Genes		4 interacting genes: MAPKAPK2 MIB1 YWHAE YWHAZ	20 interacting genes: AZI2 BLM CABLES1 CEP131 CHST9 DAB2 DAPK1 EPB41L4A GABARAP JAG1 RMC1 SNX5 TBK1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2N UBE2U UBE2W
Entrez ID		22994	57534
HPRD ID		16532	06660
Ensembl ID		ENSG00000141577	ENSG00000101752
Uniprot IDs		I3L2J8 Q9UPN4	Q86YT6
PDB IDs			4TSE 4XI6 4XI7 4XIB
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?