TPX2 and NAP1L1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		TPX2	NAP1L1
Description		TPX2 microtubule nucleation factor	nucleosome assembly protein 1 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Spindle Cytosol Microtubule Microtubule Cytoskeleton Axon Hillock Intercellular Bridge Mitotic Spindle	Nucleus Cytoplasm Membrane Melanosome
	Molecular Function	Protein Binding Protein Kinase Binding Importin-alpha Family Protein Binding	RNA Binding Protein Binding
	Biological Process	Mitotic Cell Cycle Apoptotic Process Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Regulation Of G2/M Transition Of Mitotic Cell Cycle Activation Of Protein Kinase Activity Cell Division Regulation Of Mitotic Spindle Organization Mitotic Spindle Assembly Regulation Of Signal Transduction By P53 Class Mediator	DNA Replication Nucleosome Assembly Positive Regulation Of Cell Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Regulation of TP53 Activity through Phosphorylation AURKA Activation by TPX2
Drugs
Diseases
GWAS		Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Prudent dietary pattern ( 28644415)	Obesity-related traits ( 23251661)
Interacting Genes		7 interacting genes: AURKA CDK6 GOLGA2 HMMR NAP1L1 SIAH2 THAP11	17 interacting genes: CREBBP CSNK2A1 CSNK2B DLST EP300 FSD1 HBA1 HMGB2 HSPB1 MED10 MTNR1A NR2F6 POT1 SP1 TERF1 TP53 TPX2
Entrez ID		22974	4673
HPRD ID		05802	01248
Ensembl ID		ENSG00000088325	ENSG00000187109
Uniprot IDs		Q643R0 Q9ULW0	A0A024RBB7 B7Z2V4 F5H4R6 F8W543 P55209 Q9H2B0
PDB IDs		1OL5 3E5A 3HA6 4C3P 5LXM 6BJC
Enriched GO Terms of Interacting Partners?
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