SHANK2 and ARHGEF7

  • Number of citations of the paper that reports this interaction (PubMedID 12626503)
  • 61
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, two hybrid, in vitro)

SHANK2

ARHGEF7

Description SH3 and multiple ankyrin repeat domains 2 Rho guanine nucleotide exchange factor 7
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder ( 31043756)
  • Hip circumference ( 28552196)
  • Late-onset Alzheimer's disease ( 27770636)
  • Obesity-related traits ( 23251661)
  • Response to fenofibrate (adiponectin levels) ( 23149075)
  • Urate levels in obese individuals ( 25811787)
  • Bilirubin levels ( 19414484)
  • Choroid plexus volume ( 31530798)
  • Fasting insulin (dietary factor interaction) ( 24204828)
  • Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828)
  • Macular thickness ( 30535121)
  • Menarche (age at onset) ( 21102462)
  • Menopause (age at onset) ( 19448619)
  • Skin aging measurement ( 31522824)
Interacting Genes 16 interacting genes: ADGRB2 ADGRL1 ADGRL2 ARHGEF7 BAIAP2 CTTN DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 DNAJC19 DNM2 SHARPIN SLC9A3 SSTR2 33 interacting genes: ADAM15 ARHGEF6 CALM1 CBLB CD244 CDC42 EGFR ERBIN GIT1 GIT2 HSPB1 ITCH LRRK2 MEOX2 NCK1 NCKIPSD NOX1 PAK1 PAK2 PAK3 PPM1E PPM1F PRKCG PXN RAC1 SCRIB SH2D1A SHANK1 SHANK2 TGFBR2 TUBB3 WAS YWHAG
Entrez ID 22941 8874
HPRD ID 04479 05688
Ensembl ID ENSG00000162105 ENSG00000102606
Uniprot IDs A0A590UJ45 A6NHU9 C0SPH0 Q9UPX8 A0A024RDY9 B7Z344 B7Z6G2 E9PDQ5 Q14155 Q5W9H1
PDB IDs 1BY1 1ZSG 2L3G 5SXP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?