SCAP and PGRMC1

Number of citations of the paper that reports this interaction (PubMedID 15782218)
103

Data Source:
HPRD (in vivo)

		SCAP	PGRMC1
Description		SREBF chaperone	progesterone receptor membrane component 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Protein-containing Complex	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse
	Molecular Function	Protein Binding Sterol Binding Protein-containing Complex Binding Unfolded Protein Binding	Amyloid-beta Binding Steroid Binding Protein Binding
	Biological Process	Response To Hypoxia Immune Response Aging Cholesterol Metabolic Process Response To Insulin SREBP Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Cellular Lipid Metabolic Process Negative Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process	Neutrophil Degranulation
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) Regulation of cholesterol biosynthesis by SREBP (SREBF)	Neutrophil degranulation
Drugs			Dextromethorphan Nortriptyline
Diseases
GWAS
Interacting Genes		12 interacting genes: ATG16L1 DHX30 HIPK2 INSIG1 INSIG2 KLHL18 LAMC2 NDUFAF3 PGRMC1 SEC24B SREBF2 WDR6	6 interacting genes: CENPU CREB3L1 GLP1R MTNR1A PAM16 SCAP
Entrez ID		22937	10857
HPRD ID		03300	02338
Ensembl ID		ENSG00000114650	ENSG00000101856
Uniprot IDs		B7Z6H0 Q12770	O00264 Q6IB11
PDB IDs			4X8Y
Enriched GO Terms of Interacting Partners?
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