DHX30 and NR2E3

Number of citations of the paper that reports this interaction (PubMedID 17255935)
32

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		DHX30	NR2E3
Description		DExH-box helicase 30	nuclear receptor subfamily 2 group E member 3
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GO Annotations	Cellular Component	Intracellular Cytoplasm Mitochondrion Cytosol Ribonucleoprotein Granule Mitochondrial Nucleoid	Nucleus Nucleoplasm Transcription Factor Complex
	Molecular Function	Chromatin Binding RNA Binding RNA Helicase Activity Double-stranded RNA Binding Protein Binding ATP Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Nuclear Receptor Activity Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Central Nervous System Development Mitochondrial Large Ribosomal Subunit Assembly	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Visual Perception Phototransduction Negative Regulation Of Cell Proliferation Cell Differentiation Intracellular Receptor Signaling Pathway Eye Photoreceptor Cell Development Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Rhodopsin Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development Retina Development In Camera-type Eye
Pathways
Drugs
Diseases			Vitreoretinal degeneration, including: Stickler syndrome type I (STL1); Stickler syndrome type II (STL2); Snowflake vitreoretinal degeneration (SVD); Wagner syndrome 1 (WGN1); Knobloch syndrome (KNO); Enhanced S-cone syndrome (ESCS); Autosomal dominant vitreoretinochoroidopathy (ADVIRC) Retinitis pigmentosa (RP)
GWAS			Macular thickness ( 30535121) Metabolite levels (HVA/MHPG ratio) ( 23319000)
Interacting Genes		18 interacting genes: CDK9 DHX58 EIF2AK2 HDAC1 HDAC3 HNRNPD MYBBP1A NCOR1 NEDD4 NR2E3 OAS3 RBBP4 RBBP7 RBL1 SCAP SIN3A SKIL TBL3	28 interacting genes: BCL11A CDK9 CRX DEDD2 DHX30 ELAVL2 HDAC1 HDAC3 HOXC13 IRF9 MYBBP1A NCOR1 NR1D1 NR3C1 NRL POLR3D PPARG RARA RBBP4 RBBP7 RBFOX2 RBL1 RXRA RXRB SIN3A SNAPC1 TBL3 ZNF232
Entrez ID		22907	10002
HPRD ID		13142	05132
Ensembl ID		ENSG00000132153	ENSG00000278570
Uniprot IDs		H7BXY3 Q7L2E3	F1D8Q9 Q9Y5X4
PDB IDs		2DB2	4LOG
Enriched GO Terms of Interacting Partners?
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