MTF2 and TMED9

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		MTF2	TMED9
Description		metal response element binding transcription factor 2	transmembrane p24 trafficking protein 9
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Focal Adhesion ESC/E(Z) Complex	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Synaptic Vesicle Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle Trans-Golgi Network Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA Binding Chromatin Binding Methylated Histone Binding Metal Ion Binding	Protein Binding Syntaxin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Segment Specification Stem Cell Population Maintenance Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription By RNA Polymerase II Stem Cell Differentiation Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation Cellular Response To Leukemia Inhibitory Factor	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Organization Positive Regulation Of Organelle Organization Protein Exit From Endoplasmic Reticulum Early Endosome To Golgi Transport COPI Coating Of Golgi Vesicle
Pathways		PRC2 methylates histones and DNA	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Bitter alcoholic beverage consumption ( 31046077) Chronotype ( 30696823) Plasma clusterin levels ( 26545630) Response to lurasidone in schizophrenia ( 29730043)	Obesity-related traits ( 23251661) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: CREB1 GPRASP1 GSK3B KDM1A PIK3R3 PRKD2 PRMT6 SMAD3 SUV39H1 SUV39H2 TMED9	8 interacting genes: CKMT2 COPZ1 DDX54 MAT2B MTF2 NMT2 SEC23B THAP8
Entrez ID		22823	54732
HPRD ID		14342	09975
Ensembl ID		ENSG00000143033	ENSG00000184840
Uniprot IDs		B4DZ69 B4DZG1 Q7Z534 Q9Y483	A0A024R7M0 Q9BVK6
PDB IDs		5XFR
Enriched GO Terms of Interacting Partners?
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