FES and IL4R

  • Number of citations of the paper that reports this interaction (PubMedID 7518439)
  • 7
  • Data Source:
  • HPRD (in vivo)

FES

IL4R

Description FES proto-oncogene, tyrosine kinase interleukin 4 receptor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Birth weight ( 31043758 27680694)
  • Blood pressure ( 21909110)
  • Coffee consumption ( 31046077)
  • Coronary artery disease ( 29212778 30104761 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Daytime sleep phenotypes ( 27126917)
  • Diastolic blood pressure ( 27841878 21909115 28739976 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Hypertension ( 31879980 21909115)
  • Ischemic stroke ( 29531354)
  • Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (beta blocking agents) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Myocardial infarction ( 26343387)
  • Number of sexual partners ( 30643258)
  • Offspring birth weight ( 31043758)
  • Pulse pressure ( 27841878 30578418)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Schizophrenia ( 25056061 29483656 30285260)
  • Stroke ( 29531354)
  • Systolic blood pressure ( 26390057 28135244 27841878 21909115 28739976 27618452 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 33 interacting genes: APP BCAR1 BCR CSF2RB DOK1 DPYSL5 EGFR FKBP4 FKBP5 HSH2D HSPA4 IL4R IRS1 IRS2 JAK1 JAK2 JAK3 MDFI NEDD4 PDE4DIP PIK3R1 PLXNA1 POT1 PPID PTGES3 RASA1 RASA3 SMURF1 STAT3 TERF1 TRIM28 ZNF746 ZNF775 22 interacting genes: ARIH2 CD40 DOK2 FES HGS IL13 IL13RA1 IL2RG IL4 INPP5D IRS1 IRS2 JAK1 JAK2 JAK3 PRKCZ PTPN11 PTPN6 RACK1 SHC1 SOCS5 STAT6
Entrez ID 2242 3566
HPRD ID 01814 00990
Ensembl ID ENSG00000182511 ENSG00000077238
Uniprot IDs A0A024RC92 P07332 B2RBY1 P24394
PDB IDs 1WQU 2DCR 3BKB 3CBL 3CD3 4DYL 4E93 6JMF 1IAR 1IRS 1ITE 3BPL 3BPN 3BPO 5E4E 6OEL
Enriched GO Terms of Interacting Partners?
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