RFX6 and SNRPB

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		RFX6	SNRPB
Description		regulatory factor X6	small nuclear ribonucleoprotein polypeptides B and B1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Telomerase Holoenzyme Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding	RNA Binding Protein Binding Telomerase RNA Binding Histone Pre-mRNA DCP Binding U1 SnRNP Binding U2 SnRNP Binding
	Biological Process	Type B Pancreatic Cell Differentiation Pancreatic A Cell Differentiation Pancreatic D Cell Differentiation Regulation Of Transcription By RNA Polymerase II Endocrine Pancreas Development Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Glucose Homeostasis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Insulin Secretion Pancreatic Epsilon Cell Differentiation	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Protein Methylation Brain Development Histone MRNA Metabolic Process RNA Splicing Import Into Nucleus
Pathways		Regulation of gene expression in beta cells	SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Creatine kinase levels ( 29403010) Diastolic blood pressure ( 27841878) Height ( 31562340) Inflammatory bowel disease ( 27569725) Lung cancer ( 28604730) Neutrophil percentage of granulocytes ( 27863252) Offspring birth weight ( 31043758) Prostate cancer ( 20676098 31562322 26443449) Serum total protein level ( 29403010)
Interacting Genes		27 interacting genes: ARNT2 CATSPER1 CCNK CYFIP1 DGCR6 DTX2 ESR2 FHL3 FRS3 HGS KIF1A LMO3 NEDD9 PITX1 PLEKHN1 PRKAA1 PRKAA2 RFX2 RFX3 RIPK3 SNRPB SNRPC SS18L1 STK16 TLE5 VPS37C ZNF688	50 interacting genes: ASCC2 BANP CALCOCO2 CD2BP2 CDKN2A CEP55 CLNS1A COIL CTDP1 DAB1 DDX20 DHX9 ERG28 EXOSC8 FBN2 FNBP4 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GIGYF2 GOLGA2 IL7R KRT40 L3MBTL3 LSM11 LSM2 LSM8 PNMA1 PRMT5 PRMT7 PSMA3 RBPMS RFX6 SKIV2L SMN1 SMN2 SMNDC1 SNRPD1 SNRPD3 SNUPN SS18L1 STRAP STXBP2 STXBP3 TFIP11 TOP3B TRIM23 WBP4 WDR77
Entrez ID		222546	6628
HPRD ID		11490	01655
Ensembl ID		ENSG00000185002	ENSG00000125835
Uniprot IDs		Q8HWS3	P14678 Q66K91
PDB IDs			1D3B 3CW1 3JCR 3PGW 4PJO 4WZJ 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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