CPNE2 and PPP5C

Number of citations of the paper that reports this interaction (PubMedID 12522145)
33

Data Source:
HPRD (two hybrid)

		CPNE2	PPP5C
Description		copine 2	protein phosphatase 5 catalytic subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytosol Plasma Membrane Protein-containing Complex Perikaryon Intracellular Membrane-bounded Organelle Chaperone Complex Proximal Dendrite
	Molecular Function	Protein Binding Calcium-dependent Phospholipid Binding	G-protein Alpha-subunit Binding RNA Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding ATP Binding Microtubule Binding Lipid Binding Phosphatase Activity Identical Protein Binding ADP Binding Protein-containing Complex Binding Metal Ion Binding Tau Protein Binding Hsp90 Protein Binding
	Biological Process	Cellular Response To Calcium Ion	MAPK Cascade Mitotic Cell Cycle Negative Regulation Of Protein Phosphorylation DNA Repair Transcription, DNA-templated Protein Dephosphorylation Response To Lead Ion Histone Dephosphorylation Peptidyl-threonine Dephosphorylation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Morphine Peptidyl-serine Dephosphorylation Cellular Response To Hydrogen Peroxide Cellular Response To Cadmium Ion Negative Regulation Of Neuron Death Response To Arachidonic Acid Positive Regulation Of Glucocorticoid Receptor Signaling Pathway
Pathways			Negative regulation of MAPK pathway Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks ESR-mediated signaling
Drugs			ATP
Diseases
GWAS			Basophil percentage of white cells ( 27863252) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Neuroticism ( 29255261) Response to antidepressants in depression ( 29998114)
Interacting Genes		18 interacting genes: ACTB ANXA7 BCOR CDKN1A IKBKG LNX1 MYCBP PDCD6 PPP5C RDX REL SKIL SORBS3 TERF2IP TRIM27 UBA3 UBE2M UBE2O	26 interacting genes: APP CDC16 CDC27 CDC37 CDK20 CHORDC1 CPNE1 CPNE2 CPNE4 CRY2 CSE1L CSNK1D DISC1 EGFR ESR2 GNA12 GNA13 HSP90AA1 HTR2A HUWE1 MAP3K5 MAP3K7 MAPT PPP2R1A PPP2R3A VHL
Entrez ID		221184	5536
HPRD ID		05015	02805
Ensembl ID		ENSG00000140848	ENSG00000011485
Uniprot IDs		Q96FN4	A0A024R0Q7 P53041
PDB IDs			1A17 1S95 1WAO 2BUG 3H60 3H61 3H62 3H63 3H64 3H66 3H67 3H68 3H69 4ZVZ 4ZX2 5HPE 5UI1 5WG8
Enriched GO Terms of Interacting Partners?
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