MARCHF8 and UBE2H

Number of citations of the paper that reports this interaction (PubMedID 30759391)
2

Data Source:
BioGRID (pull down)

		MARCHF8	UBE2H
Description		membrane associated ring-CH-type finger 8	ubiquitin conjugating enzyme E2 H
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GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Endosome Integral Component Of Membrane Cytoplasmic Vesicle Membrane Early Endosome Membrane Late Endosome Membrane	Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding MHC Protein Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination Adaptive Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Immune Response	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination
Pathways			Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Estimated glomerular filtration rate ( 31152163 31451708) Response to antidepressants and depression ( 27622933)
Interacting Genes		5 interacting genes: CD86 IL1RAP UBE2D1 UBE2D3 UBE2H	67 interacting genes: BRAP BYSL CBLC CD99 CDK2 DTX3 DTX3L DZIP3 EPS15 GOLGA2 H2AC18 HBP1 HDAC6 JADE1 LNX2 LRSAM1 MAEA MARCHF1 MARCHF10 MARCHF2 MARCHF4 MARCHF8 MKRN3 NEURL1 NHLRC1 POLL POLM PRKN PSME3 RAG1 RELA RNF10 RNF103 RNF113B RNF114 RNF128 RNF133 RNF139 RNF144A RNF146 RNF166 RNF185 RNF186 RNF2 RNF34 RNF38 RNF4 RNF6 STAM2 TLE5 TRAIP TRIM17 TRIM2 TRIM21 TRIM23 TRIM27 TRIM28 TRIM36 TRIM37 TRIM5 TRIM56 TRIM69 UBA1 UBASH3B UBOX5 UBR2 UBR3
Entrez ID		220972	7328
HPRD ID		17466	03052
Ensembl ID		ENSG00000165406	ENSG00000186591
Uniprot IDs		A0A024R7U2 Q5T0T0	A0A3B3IU20 A4D1L5 P62256
PDB IDs		2D8S	2Z5D
Enriched GO Terms of Interacting Partners?
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