STX2 and CPLX2

Number of citations of the paper that reports this interaction (PubMedID 10777504)
64

Data Source:
HPRD (in vivo, in vitro)

		STX2	CPLX2
Description		syntaxin 2	complexin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Protein-containing Complex Presynaptic Membrane Intracellular Membrane-bounded Organelle Presynaptic Active Zone Membrane	Nucleus Cytosol Cell Junction Dendrite SNARE Complex Mast Cell Granule Terminal Bouton Perikaryon Calyx Of Held Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-3-complexin Complex Postsynapse Glutamatergic Synapse
	Molecular Function	SNARE Binding Structural Molecule Activity SNAP Receptor Activity Protein Binding Calcium-dependent Protein Binding	SNARE Binding Syntaxin-1 Binding Calcium-dependent Protein Binding
	Biological Process	Intracellular Protein Transport Exocytosis Vesicle Fusion Signal Transduction Acrosome Reaction Ectoderm Development Animal Organ Morphogenesis Cell Differentiation Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cellular Response To Oxidative Stress Vesicle Docking Cornified Envelope Assembly	Vesicle Docking Involved In Exocytosis Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Exocytosis Cell Differentiation Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Positive Regulation Of Synaptic Plasticity Mast Cell Degranulation Regulation Of Neurotransmitter Secretion
Pathways
Drugs
Diseases
GWAS		Initial pursuit acceleration in psychotic disorders ( 29064472) Metabolite levels ( 23823483) Plasma plasminogen activator levels ( 24578379) vWF levels ( 30586737)	Age-related nuclear cataracts ( 24951543) Chronotype ( 30696823) Obesity-related traits ( 23251661)
Interacting Genes		10 interacting genes: CPLX2 SNAP25 STXBP1 STXBP2 SYT1 SYT4 SYT7 UNC13B VAMP3 VAPB	3 interacting genes: APP STX2 STX3
Entrez ID		2054	10814
HPRD ID		11816	09234
Ensembl ID		ENSG00000111450	ENSG00000145920
Uniprot IDs		P32856	Q6PUV4
PDB IDs
Enriched GO Terms of Interacting Partners?
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