EPHB6 and EFNB2

Number of citations of the paper that reports this interaction (PubMedID 10648835)
7

Data Source:
HPRD (in vitro, in vivo)

		EPHB6	EFNB2
Description		EPH receptor B6	ephrin B2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Plasma Membrane Integral Component Of Plasma Membrane Adherens Junction Focal Adhesion Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Integral Component Of Presynaptic Membrane Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity ATP Binding Signaling Receptor Activity	Virus Receptor Activity Protein Binding Ephrin Receptor Binding
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Peptidyl-tyrosine Phosphorylation Positive Regulation Of Kinase Activity Ephrin Receptor Signaling Pathway	Lymph Vessel Development Cell Migration Involved In Sprouting Angiogenesis Cell Adhesion Cell-cell Signaling Axon Guidance Positive Regulation Of Cell Proliferation Anatomical Structure Morphogenesis Animal Organ Morphogenesis Negative Regulation Of Keratinocyte Proliferation Negative Regulation Of Neuron Projection Development T Cell Costimulation Adherens Junction Organization Viral Entry Into Host Cell Ephrin Receptor Signaling Pathway Blood Vessel Morphogenesis Venous Blood Vessel Morphogenesis Regulation Of Chemotaxis Nephric Duct Morphogenesis Presynapse Assembly Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Positive Regulation Of Neuron Death Positive Regulation Of Aorta Morphogenesis Positive Regulation Of Cardiac Muscle Cell Differentiation
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells	EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Cancer ( 29299148)	Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Metabolite levels ( 23823483) Pediatric autoimmune diseases ( 26301688) Subcutaneous adipose tissue ( 26480920)
Interacting Genes		19 interacting genes: AFDN CBL CRK CRKL DUSP18 DUSP19 EFNB2 EPHB1 ERBB2 GRB2 HDHD2 INCA1 NIF3L1 NOTCH2NLA REL SAT1 STYX TCF4 TRIM39	21 interacting genes: DLG4 EPHA3 EPHA4 EPHB1 EPHB2 EPHB4 EPHB6 GRIP1 GRM1 GRM5 HOMER1 NCK2 PDZRN3 PECAM1 PICK1 PSEN1 PTPN13 RGS3 RHBDL2 SDCBP SRC
Entrez ID		2051	1948
HPRD ID		04133	02754
Ensembl ID		ENSG00000106123	ENSG00000125266
Uniprot IDs		F8WCM8 J3KQU5 O15197	P52799
PDB IDs			2HLE 2I85 2VSK 2VSM 2WO2 3GXU 4UF7 6P7Y 6PDL
Enriched GO Terms of Interacting Partners?
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