EPHA8 and EFNA4

Number of citations of the paper that reports this interaction (PubMedID 10515610)
1

Data Source:
HPRD (in vivo)

		EPHA8	EFNA4
Description		EPH receptor A8	ephrin A4
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Early Endosome Membrane Neuron Projection Receptor Complex	Extracellular Region Plasma Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity GPI-linked Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity ATP Binding	Transmembrane-ephrin Receptor Activity Protein Binding Ephrin Receptor Binding
	Biological Process	Substrate-dependent Cell Migration Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axon Guidance Neuron Remodeling Peptidyl-tyrosine Phosphorylation Regulation Of Cell Adhesion Neuron Projection Development Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of Phosphatidylinositol 3-kinase Activity Protein Autophosphorylation Ephrin Receptor Signaling Pathway Cellular Response To Follicle-stimulating Hormone Stimulus	Cell-cell Signaling Axon Guidance Osteoclast Differentiation Bone Remodeling Ephrin Receptor Signaling Pathway
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells EPH-ephrin mediated repulsion of cells	EPH-Ephrin signaling EPH-Ephrin signaling EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells EPH-ephrin mediated repulsion of cells
Drugs
Diseases
GWAS			Adventurousness ( 30643258) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Prostate cancer ( 23535732)
Interacting Genes		12 interacting genes: AK4 DARS2 EFNA1 EFNA4 EFNA5 FYN G3BP1 LRRK1 PIK3CG PSMC5 PTPRD ZNF746	9 interacting genes: EPHA2 EPHA3 EPHA4 EPHA5 EPHA6 EPHA7 EPHA8 ITGB1 MAP2K4
Entrez ID		2046	1945
HPRD ID		01493	03224
Ensembl ID		ENSG00000070886	ENSG00000243364
Uniprot IDs		P29322	P52798
PDB IDs		1UCV 1X5L 3KUL
Enriched GO Terms of Interacting Partners?
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