TUBB and ATXN3

  • Number of citations of the paper that reports this interaction (PubMedID 24685680)
  • 6
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

TUBB

ATXN3

Description tubulin beta class I ataxin 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Blood protein levels ( 28240269)
  • Decreased fine motor function in Charcot-Marie-Tooth disease 1A (eating with utensils) ( 30958311)
  • Handedness (non-right-handed vs right-handed) ( 31504236)
  • Amyotrophic lateral sclerosis ( 29566793)
  • Coronary artery calcification ( 23870195)
  • HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
  • Height ( 18391950 18391951)
  • LDL cholesterol levels x loop diuretics use interaction ( 31806883)
  • Orofacial clefts ( 22419666)
Interacting Genes 71 interacting genes: ADAP2 ALDOA APP ARL8B ATXN3 B4GALT1 BMPR2 BRCA1 CDKN2A CLIP1 CMTM5 CNN1 CRIPT DISC1 DPYSL2 DYNLL1 ESR1 GDAP1 GRM1 HDAC6 HGS HTRA2 HTT LNX2 MAGEA2B MAL2 MAP1A MAP3K10 MAP4 MAP6 MAPRE1 MAPT MARK4 MRGBP MTNR1A MX1 NCALD NCAM1 NCAPH2 NDEL1 NPHP1 PFDN4 PLK1 PRKN PTEN RAB8B RACK1 RASSF1 S100A8 S100A9 SDC3 SPP1 STAU1 SUMO2 SYT9 TAOK2 TBCD TGM2 TINF2 TPPP TTBK1 TTK TUBA1A VAV1 YWHAB YWHAG YWHAQ YWHAZ ZAP70 ZFYVE21 ZMYND19 50 interacting genes: ANXA7 APP ARHGAP19 ARHGDIA ASIC1 C16orf70 CAPN1 CAPN2 CASP1 CDKN1A CHEK1 CSNK2B DNM2 EWSR1 GSK3B HDAC6 KAT2B MAP3K1 MKNK1 NCOR1 NEDD8 PICK1 PJA1 PRKN PSMD7 RAD23A RAD23B RFFL RPS6KA1 SMURF1 SQSTM1 STUB1 SUMO1 TEX11 TK1 TP53 TRAF6 TRIM54 TRIM55 TRIM63 TUBA1A TUBB UBB UBC UBE2L3 UBE2S UBE4B UBQLN1 USP21 VCP
Entrez ID 203068 4287
HPRD ID 01852 06131
Ensembl ID ENSG00000196230 ENSG00000066427
Uniprot IDs B4DMJ5 B4DQN9 B4DY90 P07437 Q5ST81 Q5SU16 A0A0A0MS38 C9JQV6 P54252
PDB IDs 3QNZ 3QO0 5N5N 6I2I 6QUS 6QUY 6QVJ 1YZB 2AGA 2DOS 2JRI 2KLZ 4WTH 4YS9
Enriched GO Terms of Interacting Partners?
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