ELK3 and ID2

Number of citations of the paper that reports this interaction (PubMedID 10022839)
38

Data Source:
HPRD (in vitro)

		ELK3	ID2
Description		ETS transcription factor ELK3	inhibitor of DNA binding 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Mitochondrion	Nucleus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Purine-rich Negative Regulatory Element Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Protein Binding Ion Channel Binding Protein Dimerization Activity Transcription Regulator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Regulation Of Transcription By RNA Polymerase II Signal Transduction Cell Differentiation Wound Healing Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Natural Killer Cell Differentiation Thigmotaxis Membranous Septum Morphogenesis Bundle Of His Development Multicellular Organism Development Adult Locomotory Behavior Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Oligodendrocyte Development Regulation Of Lipid Metabolic Process Olfactory Bulb Development Cell Differentiation Circadian Regulation Of Gene Expression Mammary Gland Epithelial Cell Proliferation Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Enucleate Erythrocyte Differentiation Negative Regulation Of DNA-binding Transcription Factor Activity Locomotor Rhythm Negative Regulation Of B Cell Differentiation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Macrophage Differentiation Regulation Of Neuron Differentiation Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Blood Pressure Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Cell Maturation Peyer's Patch Development Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Neuron Fate Commitment Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Astrocyte Differentiation Negative Regulation Of Oligodendrocyte Differentiation Adipose Tissue Development Mammary Gland Alveolus Development Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Endodermal Digestive Tract Morphogenesis Positive Regulation Of Cell Cycle Arrest Cellular Response To Lithium Ion Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Senescence Negative Regulation Of Core Promoter Binding Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Neural Precursor Cell Proliferation
Pathways			NGF-stimulated transcription
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia in childhood (B cell precursor) ( 29632299 27694927) B-cell acute lymphoblastic leukaemia ( 31767839) Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382) Small intestine neuroendocrine tumor ( 27492634)	Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 27182965) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Cognitive decline rate in late mild cognitive impairment ( 26252872) IgE levels ( 22075330) Itch intensity from mosquito bite ( 28199695) Mean corpuscular volume ( 28017375) PR interval ( 29127183 30046033 31217584) Self-reported allergy ( 23817569)
Interacting Genes		10 interacting genes: APP CRK CTBP1 ID2 MAPK14 MAPK8 MAPK9 PIAS1 TCF3 TOP1	44 interacting genes: ADD1 ASB4 CDK2 DYRK1A DYRK1B ELK1 ELK3 ELK4 ELOC GATA4 HES1 IFI16 KDM1A LRIF1 MAPK1 MAPK3 MAPK8 MSC MYF5 MYF6 MYOD1 MYOG NEDD9 NR0B2 PAX2 PAX5 PAX8 PPP1CA PRMT6 RB1 RBL1 RBL2 RBM48 RHOU RIN3 SREBF1 SUV39H1 SUV39H2 TCF12 TCF3 TCF4 TNS2 TSTA3 UNC119
Entrez ID		2004	3398
HPRD ID		02593	02664
Ensembl ID		ENSG00000111145	ENSG00000115738
Uniprot IDs		A0A024RBE2 P41970	Q02363 Q53T66
PDB IDs			4AYA
Enriched GO Terms of Interacting Partners?
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