ELK1 and TAOK2

Number of citations of the paper that reports this interaction (PubMedID 12665513)
12

Data Source:
HPRD (in vitro)

		ELK1	TAOK2
Description		ETS transcription factor ELK1	TAO kinase 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Mitochondrion Dendrite Neuronal Cell Body Axon Terminus	Nucleoplasm Nucleolus Cytoplasm Cytosol Actin Cytoskeleton Integral Component Of Membrane Axon Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Receptor Complex Dendritic Growth Cone Axonal Growth Cone
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity ATP Binding Mitogen-activated Protein Kinase Kinase Binding Neuropilin Binding Tau Protein Binding Tau-protein Kinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Response To Light Stimulus Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Testosterone Stimulus Cellular Response To Gamma Radiation Response To Fibroblast Growth Factor Positive Regulation Of Neuron Death	Activation Of MAPKK Activity Activation Of MAPK Activity Regulation Of Cell Growth Protein Targeting To Membrane Apoptotic Process Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Regulation Of Mitotic Cell Cycle Axonogenesis Regulation Of Cell Shape Cell Migration Signal Transduction By Protein Phosphorylation Actin Cytoskeleton Organization Stress-activated Protein Kinase Signaling Cascade G2 DNA Damage Checkpoint Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Positive Regulation Of Stress-activated MAPK Cascade Regulation Of Actin Cytoskeleton Organization Positive Regulation Of JNK Cascade Protein Autophosphorylation Focal Adhesion Assembly Stress-activated MAPK Cascade Basal Dendrite Morphogenesis Basal Dendrite Arborization
Pathways		ERK/MAPK targets NGF-stimulated transcription HCMV Early Events Estrogen-dependent nuclear events downstream of ESR-membrane signaling Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Drugs			Dexfosfoserine
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Body mass index ( 29273807) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Metabolic syndrome ( 31589552) Schizophrenia ( 28991256 25056061 29483656 30285260)
Interacting Genes		40 interacting genes: AKAP8 APP BRCA1 CDK6 CEBPB CREBBP CRK EMX1 EP300 EWSR1 FBXO25 FLI1 FOS GRB10 GRB2 HDAC1 HOXB13 ID1 ID2 ID3 KLF4 MAD2L2 MAP2K1 MAP2K3 MAPK1 MAPK10 MAPK11 MAPK14 MAPK3 MAPK8 MAPK9 MOB4 PIAS2 PLCG2 SNCA SRF STARD3NL STK16 TAOK2 UBE2I	12 interacting genes: BCKDK ELK1 KLHL12 MAP2K3 MAP2K6 MEGF10 RCHY1 TLE3 TUBA1A TUBA4A TUBB USF1
Entrez ID		2002	9344
HPRD ID		02407	18147
Ensembl ID		ENSG00000126767	ENSG00000149930
Uniprot IDs		A0A024R1A7 P19419 Q86SR6	Q9UL54
PDB IDs		1DUX 5VVT
Enriched GO Terms of Interacting Partners?
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