CELSR3 and SPTBN2

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		CELSR3	SPTBN2
Description		cadherin EGF LAG seven-pass G-type receptor 3	spectrin beta, non-erythrocytic 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Space Cytosol Spectrin Apical Plasma Membrane Cell Junction Neuronal Cell Body Parallel Fiber To Purkinje Cell Synapse Presynapse Glutamatergic Synapse Postsynaptic Spectrin-associated Cytoskeleton
	Molecular Function	G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding	Actin Binding Structural Constituent Of Cytoskeleton Phospholipid Binding Cadherin Binding Structural Constituent Of Synapse
	Biological Process	Neuron Migration Regulation Of Protein Phosphorylation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules G Protein-coupled Receptor Signaling Pathway Axonal Fasciculation Regulation Of Protein Localization Dopaminergic Neuron Axon Guidance Serotonergic Neuron Axon Guidance Wnt Signaling Pathway, Planar Cell Polarity Pathway Cilium Assembly Cell-cell Adhesion Planar Cell Polarity Pathway Involved In Axon Guidance	MAPK Cascade ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Axon Guidance Synapse Assembly Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cerebellar Purkinje Cell Layer Morphogenesis Adult Behavior Multicellular Organism Growth Actin Filament Capping Postsynapse Organization
Pathways			MHC class II antigen presentation NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade COPI-mediated anterograde transport
Drugs
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Blood protein levels ( 28240269) Cognitive ability (MTAG) ( 29186694) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Mental health study participation (provided email address) ( 31263887) Ulcerative colitis ( 28067908)	Bipolar disorder ( 28115744 21926972 31043756)
Interacting Genes		12 interacting genes: CLK1 CLUH DST IFT140 SCAPER SGSM2 SPTBN2 SPTBN4 SWAP70 TRIP12 TSPYL4 UACA	10 interacting genes: ACTA1 ACTB ACTR1A APC CELSR3 DCTN1 MINK1 SPTA1 SPTAN1 UNC13B
Entrez ID		1951	6712
HPRD ID		09179	05404
Ensembl ID		ENSG00000008300	ENSG00000173898
Uniprot IDs		Q9NYQ7	O15020
PDB IDs			1WJM 1WYQ 6ANU
Enriched GO Terms of Interacting Partners?
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