EFNB1 and CAPN10

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		EFNB1	CAPN10
Description		ephrin B1	calpain 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Raft Synapse Extracellular Exosome	Cytoplasm Mitochondrion Cytosol Plasma Membrane
	Molecular Function	Protein Binding Ephrin Receptor Binding	SNARE Binding Calcium-dependent Cysteine-type Endopeptidase Activity Cytoskeletal Protein Binding
	Biological Process	Neural Crest Cell Migration Cell Adhesion Cell-cell Signaling Axon Guidance Embryonic Pattern Specification T Cell Costimulation Positive Regulation Of T Cell Proliferation Ephrin Receptor Signaling Pathway	Proteolysis Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Actin Cytoskeleton Reorganization Positive Regulation Of Insulin Secretion Positive Regulation Of Intracellular Transport Cellular Response To Insulin Stimulus Positive Regulation Of Glucose Import Type B Pancreatic Cell Apoptotic Process Positive Regulation Of Type B Pancreatic Cell Apoptotic Process
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells	Degradation of the extracellular matrix
Drugs
Diseases		Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome	Type II diabetes mellitus
GWAS
Interacting Genes		17 interacting genes: CAPN10 CUL3 DNAJC5 EPHA3 EPHB1 EPHB2 GRIP1 MYC NCK2 PICK1 PTPN13 RGS3 SDCBP SORBS1 SRC TIAM1 YWHAQ	5 interacting genes: EFNB1 FANCC FLOT1 PSMA7 SHD
Entrez ID		1947	11132
HPRD ID		02072	05595
Ensembl ID		ENSG00000090776	ENSG00000142330
Uniprot IDs		P98172	Q9HC96
PDB IDs
Enriched GO Terms of Interacting Partners?
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