ECT2 and ERAL1

Number of citations of the paper that reports this interaction (PubMedID 22990118)
46

Data Source:
BioGRID (two hybrid)

		ECT2	ERAL1
Description		epithelial cell transforming 2	Era like 12S mitochondrial rRNA chaperone 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cell-cell Junction Bicellular Tight Junction Nuclear Body Midbody Cleavage Furrow Mitotic Spindle Centralspindlin Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Protein Homodimerization Activity	RNA Binding Protein Binding GTP Binding RRNA Binding Ribosomal Small Subunit Binding
	Biological Process	Mitotic Cytokinesis Cell Morphogenesis G Protein-coupled Receptor Signaling Pathway Protein Transport Activation Of Protein Kinase Activity Positive Regulation Of Cytokinesis Intracellular Signal Transduction Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of GTPase Activity Positive Regulation Of Neuron Differentiation Regulation Of Protein Kinase Activity Regulation Of Small GTPase Mediated Signal Transduction Protein Homooligomerization Regulation Of Attachment Of Spindle Microtubules To Kinetochore Cellular Response To Hydrogen Peroxide Bicellular Tight Junction Assembly Cellular Response To Calcium Ion Cellular Response To Ionizing Radiation Activation Of GTPase Activity Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly	Ribosomal Small Subunit Assembly Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Estimated glomerular filtration rate reduction (30%) ( 30955190) Glycated hemoglobin levels ( 28898252) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 28017375) Mean corpuscular volume ( 29403010) Pulse pressure ( 30224653)
Interacting Genes		37 interacting genes: ABR C2orf42 CCDC91 CD19 CDK1 CHST10 CSTB EIF4A2 EIF5B ELOC ERAL1 F2RL2 FANCM GGN ILVBL KLHL20 MBD1 MT-CO2 MT2A NOMO1 NPC2 OOSP2 OTUB1 PARD6A PCOLCE PLK1 POMP PSMA6 RACGAP1 RHOG RPS20 SNRNP200 SPATA22 SRPK2 THAP11 UBB VDAC2	3 interacting genes: CEP44 ECT2 TMEM97
Entrez ID		1894	26284
HPRD ID		11860	08466
Ensembl ID		ENSG00000114346	ENSG00000132591
Uniprot IDs		Q9H8V3	O75616
PDB IDs		3L46 4N40
Enriched GO Terms of Interacting Partners?
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