ECH1 and CSTF2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ECH1	CSTF2
Description		enoyl-CoA hydratase 1	cleavage stimulation factor subunit 2
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GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Matrix Cytosol Membrane Extracellular Exosome	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body
	Molecular Function	Protein Binding Delta3,5-delta2,4-dienoyl-CoA Isomerase Activity	RNA Binding MRNA Binding Protein Binding
	Biological Process	Protein Targeting To Peroxisome Fatty Acid Beta-oxidation	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation
Pathways		Peroxisomal protein import Peroxisomal protein import	tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		11 interacting genes: APP CSTF2 EEF1D EEF1G FAM9B HTT PAFAH1B3 SERPINB9 STAT3 TIMP1 TLR10	23 interacting genes: APP BAG6 CEP126 CHD3 CSTF3 DDX1 ECH1 EEF1G ELP1 ERG28 FEZ1 HGS IMMT KAT5 POLR2A SPAG8 SS18L1 SUB1 SYMPK TFG UBQLN1 UBQLN4 ZNF341
Entrez ID		1891	1478
HPRD ID		02825	02652
Ensembl ID		ENSG00000104823	ENSG00000101811
Uniprot IDs		A0A384MR44 Q13011	B3V096 B4DUD5 E7EWR4 P33240
PDB IDs		2VRE	1P1T 2J8P
Enriched GO Terms of Interacting Partners?
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