E2F3 and TFE3

Number of citations of the paper that reports this interaction (PubMedID 12748276)
45

Data Source:
BioGRID (two hybrid, pull down, affinity chromatography technology)
HPRD (in vivo, in vitro, two hybrid)

		E2F3	TFE3
Description		E2F transcription factor 3	transcription factor binding to IGHM enhancer 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Factor Complex	Nuclear Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding Bacterial-type RNA Polymerase Transcriptional Activator Activity, Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Protein Dimerization Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding Protein Dimerization Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Import Into Nucleus Positive Regulation Of Cell Proliferation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Negative Regulation Of Fat Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process	Adaptive Immune Response Humoral Immune Response Regulation Of Osteoclast Differentiation Positive Regulation Of Cell Adhesion Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cold-induced Thermogenesis
Pathways		Pre-NOTCH Transcription and Translation Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence CDC6 association with the ORC:origin complex G2 Phase Cyclin D associated events in G1
Drugs
Diseases			Alveolar soft part sarcoma Renal cell carcinoma
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708) Metabolite levels ( 23823483) Molybdenum levels ( 26025379) Obesity-related traits ( 23251661)
Interacting Genes		25 interacting genes: ATAD2 CCNA2 CDK3 CREBBP DNMT3L FHL2 FZR1 HCFC1 HELLS MGA MYBL2 PKIB RB1 RNF144A RYBP SP1 SPIB SRA1 TEAD3 TFDP1 TFDP2 TFE3 UCHL5 WNK1 YY1	9 interacting genes: E2F3 HMGB1 MITF SMAD3 SMAD4 SMARCE1 TFEB TFEC YWHAG
Entrez ID		1871	7030
HPRD ID		02693	02439
Ensembl ID		ENSG00000112242	ENSG00000068323
Uniprot IDs		O00716	A0A024QZ23 B4DIA5 P19532
PDB IDs
Enriched GO Terms of Interacting Partners?
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