TRDMT1 and GBE1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		TRDMT1	GBE1
Description		tRNA aspartic acid methyltransferase 1	1,4-alpha-glucan branching enzyme 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	RNA Binding TRNA Methyltransferase Activity TRNA (cytosine-5-)-methyltransferase Activity	1,4-alpha-glucan Branching Enzyme Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Protein Binding Cation Binding 1,4-alpha-glucan Branching Enzyme Activity (using A Glucosylated Glycogenin As Primer For Glycogen Synthesis)
	Biological Process	Response To Amphetamine TRNA Modification TRNA Methylation TRNA Stabilization	Carbohydrate Metabolic Process Glycogen Metabolic Process Glycogen Biosynthetic Process Generation Of Precursor Metabolites And Energy
Pathways		tRNA modification in the nucleus and cytosol	Glycogen synthesis Glycogen storage disease type IV (GBE1)
Drugs		Pentamidine S-adenosyl-L-homocysteine Glycerin
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Telomere length ( 24478790)	Body mass index ( 25673413) Cadmium levels ( 26025379) Chronotype ( 30696823) Extraversion ( 27918536) Hand grip strength ( 29691431) Intraocular pressure ( 31798171) Intraocular pressure and central corneal thickness (multi-trait analysis) ( 31798171) Iron status biomarkers (transferrin saturation) ( 28334935) Lead levels in blood ( 25820613) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Photic sneeze reflex ( 30899065) Risk-taking tendency (4-domain principal component model) ( 30643258) Waist circumference ( 25673412)
Interacting Genes		14 interacting genes: APP COPS6 DDX24 EEF1A1 GBE1 LRIF1 NFRKB RBM48 SETDB1 SNRPD3 STX1A TBC1D2B UNC119 UTP14A	6 interacting genes: EPHB3 PDE4DIP PGD PRMT6 RIPK3 TRDMT1
Entrez ID		1787	2632
HPRD ID		16001	01985
Ensembl ID		ENSG00000107614	ENSG00000114480
Uniprot IDs		A0A0U1U562 B4DQZ2 O14717 Q6ICS7 Q7Z3E4	Q04446 Q59ET0
PDB IDs		1G55	4BZY 5CLT 5CLW
Enriched GO Terms of Interacting Partners?
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