DMBT1 and SFTPD

Number of citations of the paper that reports this interaction (PubMedID 9153228)
54

Data Source:
BioGRID (biochemical, pull down, pull down)
HPRD (in vitro)

		DMBT1	SFTPD
Description		deleted in malignant brain tumors 1	surfactant protein D
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm External Side Of Plasma Membrane Extrinsic Component Of Membrane Phagocytic Vesicle Membrane Extracellular Matrix Zymogen Granule Membrane Extracellular Exosome	Extracellular Region Collagen Trimer Extracellular Space Lysosome Multivesicular Body Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Endocytic Vesicle Clathrin-coated Endocytic Vesicle
	Molecular Function	Scavenger Receptor Activity Protein Binding Zymogen Binding Pattern Recognition Receptor Activity Calcium-dependent Protein Binding	Lipopolysaccharide Binding Protein Binding Carbohydrate Binding Identical Protein Binding Monosaccharide Binding
	Biological Process	Endocytosis Multicellular Organism Development Protein Transport Viral Process Epithelial Cell Differentiation Induction Of Bacterial Agglutination Cellular Protein Metabolic Process Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Virus	Regulation Of Cytokine Production Toll-like Receptor Signaling Pathway Receptor-mediated Endocytosis Respiratory Gaseous Exchange Developmental Process Negative Regulation Of T Cell Proliferation Defense Response To Bacterium Surfactant Homeostasis Induction Of Bacterial Agglutination Cellular Protein Metabolic Process Negative Regulation Of Interleukin-2 Biosynthetic Process Innate Immune Response Macrophage Chemotaxis Lung Alveolus Development Positive Regulation Of Phagocytosis Regulation Of Immune Response Negative Regulation By Host Of Symbiont Molecular Function Reactive Oxygen Species Metabolic Process Regulation Of Adhesion Of Symbiont To Host Epithelial Cell
Pathways		Surfactant metabolism	Toll Like Receptor 4 (TLR4) Cascade Toll Like Receptor TLR1:TLR2 Cascade Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Signal regulatory protein family interactions Surfactant metabolism Regulation of TLR by endogenous ligand Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
Drugs			Beta-D-Glucose
Diseases
GWAS		Iris heterochromicity ( 30895295)	Chronic obstructive pulmonary disease ( 28166215 30804561) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Lung function (FEV1/FVC) ( 30804560) Rheumatoid arthritis ( 30423114 24390342)
Interacting Genes		2 interacting genes: SFTPA1 SFTPD	4 interacting genes: DCN DMBT1 MFAP4 RBX1
Entrez ID		1755	6441
HPRD ID		03575	01522
Ensembl ID		ENSG00000187908	ENSG00000133661
Uniprot IDs		A0A590UJ76 Q9UGM3	P35247
PDB IDs			1B08 1M7L 1PW9 1PWB 2GGU 2GGX 2ORJ 2ORK 2OS9 2RIA 2RIB 2RIC 2RID 2RIE 3DBZ 3G81 3G83 3G84 3IKN 3IKP 3IKQ 3IKR 4E52 4M17 4M18 5OXR 5OXS
Enriched GO Terms of Interacting Partners?
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