DLX5 and HOXC8

Number of citations of the paper that reports this interaction (PubMedID 9111364)
76

Data Source:
BioGRID (pull down)

		DLX5	HOXC8
Description		distal-less homeobox 5	homeobox C8
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm	Nuclear Chromatin Nucleoplasm Microtubule Cytoskeleton
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding HMG Box Domain Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding
	Biological Process	Skeletal System Development Osteoblast Differentiation Endochondral Ossification Regulation Of Transcription By RNA Polymerase II Nervous System Development Cell Proliferation Embryo Development Olfactory Bulb Interneuron Differentiation Cell Differentiation Embryonic Limb Morphogenesis BMP Signaling Pathway Epithelial Cell Differentiation Inner Ear Morphogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Formation Involved In Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Roof Of Mouth Development Olfactory Pit Development Face Morphogenesis Cellular Response To BMP Stimulus Positive Regulation Of Canonical Wnt Signaling Pathway Interneuron Axon Guidance Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus	Negative Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Neuron Differentiation Skeletal System Morphogenesis
Pathways		Regulation of RUNX2 expression and activity
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549 28869591) Morning vs. evening chronotype ( 26835600)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		9 interacting genes: DLX2 HOXC8 MAGED1 MSX1 MSX2 NCOA2 SOX10 SOX8 SPEN	12 interacting genes: BMPR1A BTG2 DLX2 DLX5 GMNN HOMEZ JUN MSX1 RBPMS SMAD1 SMAD4 SMAD6
Entrez ID		1749	3224
HPRD ID		02492	00856
Ensembl ID		ENSG00000105880	ENSG00000037965
Uniprot IDs		P56178 Q53Y73	P31273
PDB IDs		2DJN 4RDU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?