FAM9A and KMT5A

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		FAM9A	KMT5A
Description		family with sequence similarity 9 member A	lysine methyltransferase 5A
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleolus	Nucleoplasm Chromosome Cytosol
	Molecular Function	Protein Binding	P53 Binding Transcription Corepressor Activity Protein Binding Lysine N-methyltransferase Activity Protein-lysine N-methyltransferase Activity Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H4-K20 Specific)
	Biological Process	Spermatogenesis Spermatid Development Meiotic Cell Cycle	Negative Regulation Of Transcription By RNA Polymerase II Cell Cycle Peptidyl-lysine Monomethylation Histone H4-K20 Methylation Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Transcription, DNA-templated Cell Division Regulation Of Signal Transduction By P53 Class Mediator
Pathways			Condensation of Prophase Chromosomes PKMTs methylate histone lysines Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965)	Autism spectrum disorder or schizophrenia ( 28540026) High density lipoprotein cholesterol levels ( 29403010)
Interacting Genes		4 interacting genes: KDM1A KMT5A PRMT1 ZDHHC17	9 interacting genes: BTRC DTL E2F2 FAM9A H4-16 TCF7L2 TP53 TWIST1 UBE2I
Entrez ID		171482	387893
HPRD ID		06506	06254
Ensembl ID		ENSG00000183304	ENSG00000183955
Uniprot IDs		Q8IZU1	E3VVS3 Q9NQR1
PDB IDs			1ZKK 2BQZ 3F9W 3F9X 3F9Y 3F9Z 4IJ8 5HQ2 5T5G 5TEG 5TH7 5V2N 5W1Y 6BOZ
Enriched GO Terms of Interacting Partners?
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