ECI1 and MAPKAP1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ECI1	MAPKAP1
Description		enoyl-CoA delta isomerase 1	MAPK associated protein 1
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Vesicle TORC2 Complex
	Molecular Function	Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Ras GTPase Binding Protein Kinase Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Fatty Acid Beta-oxidation	Substantia Nigra Development Establishment Or Maintenance Of Actin Cytoskeleton Polarity Activation Of Protein Kinase B Activity Positive Regulation Of Peptidyl-serine Phosphorylation TORC2 Signaling Negative Regulation Of Ras Protein Signal Transduction Regulation Of Cellular Response To Oxidative Stress
Pathways		mitochondrial fatty acid beta-oxidation of unsaturated fatty acids	PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation
Drugs		Octanoyl-Coenzyme A Benzamidine
Diseases
GWAS		Anthropometric traits (multi-trait analysis) ( 30166351)	Body mass index ( 28892062) Diverticular disease ( 30177863) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Medication use (calcium channel blockers) ( 31015401) Resting heart rate ( 27798624) Sleep duration ( 30531941) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		3 interacting genes: APP MAPKAP1 POT1	9 interacting genes: ABCB1 AKT1 CDC42EP1 ECI1 MAPK8 NRAS PRKCA SGK1 YWHAG
Entrez ID		1632	79109
HPRD ID		02628	17464
Ensembl ID		ENSG00000167969	ENSG00000119487
Uniprot IDs		A0A384NKJ3 P42126	A0A024R863 Q9BPZ7
PDB IDs		1SG4	3VOQ 5ZCS
Enriched GO Terms of Interacting Partners?
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