DBT and ACADM

		DBT	ACADM
Description		dihydrolipoamide branched chain transacylase E2	acyl-CoA dehydrogenase medium chain
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Mitochondrial Alpha-ketoglutarate Dehydrogenase Complex Mitochondrial Nucleoid	Nucleus Mitochondrion Mitochondrial Matrix Axon Mitochondrial Membrane
	Molecular Function	Acetyltransferase Activity Lipoic Acid Binding Ubiquitin Protein Ligase Binding Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase Activity	Acyl-CoA Dehydrogenase Activity Identical Protein Binding Flavin Adenine Dinucleotide Binding Medium-chain-acyl-CoA Dehydrogenase Activity
	Biological Process	Branched-chain Amino Acid Catabolic Process	Fatty Acid Beta-oxidation Regulation Of Lipid Metabolic Process Carnitine Metabolic Process, CoA-linked Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase Carnitine Biosynthetic Process Medium-chain Fatty Acid Metabolic Process Medium-chain Fatty Acid Catabolic Process Oxidation-reduction Process
Pathways		Glyoxylate metabolism and glycine degradation Branched-chain amino acid catabolism	PPARA activates gene expression mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA
Drugs			Octanoyl-Coenzyme A Flavin adenine dinucleotide 3-Thiaoctanoyl-Coenzyme A
Diseases		Maple syrup urine disease (MSUD)	Disorders of fatty-acid oxidation, including: Medium-chain (MC) acyl-CoA dehydrogenase (AD) deficiency (MCADD); Short-chain AD deficiency (SCADD) ; Short-branched-chain AD deficiency (SBCADD) ; Very long-chain AD deficiency (VLCADD) ; Long-chain 3-hydroxyacyl CoA dehydrogenase deficiency (LCHADD) ; Trifunctional protein deficiency (TFP); Carnitine palmitoyltransferase deficiency (CPT); Carnitine-acylcarnitine translocase deficiency (CACT); Systemic primary carnitine deficiency (CDSP)
GWAS		Lung cancer in ever smokers ( 28604730)	Acylcarnitine levels ( 26068415) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Daytime sleep phenotypes ( 27126917) Glycine levels ( 31070104 30837465) Metabolic traits ( 21886157) Metabolite levels ( 20037589) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 23093944) Serum metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		1 interacting genes: ACADM	7 interacting genes: ABCD3 AGTR1 CALM1 DBT DIRAS3 MSH4 SUMO4
Entrez ID		1629	34
HPRD ID		02010	08447
Ensembl ID		ENSG00000137992	ENSG00000117054
Uniprot IDs		P11182	A0A0S2Z366 B4DJE7 B7Z9I1 P11310 Q5HYG7 Q5T4U5
PDB IDs		1K8M 1K8O 1ZWV 2COO 3RNM	1EGC 1EGD 1EGE 1T9G 2A1T 4P13
Enriched GO Terms of Interacting Partners?
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