AARS1 and EEF1B2

Number of citations of the paper that reports this interaction (PubMedID 11829477)
12

Data Source:
HPRD (two hybrid)

		AARS1	EEF1B2
Description		alanyl-tRNA synthetase 1	eukaryotic translation elongation factor 1 beta 2
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Membrane Extracellular Exosome	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex
	Molecular Function	TRNA Binding Aminoacyl-tRNA Editing Activity Ser-tRNA(Ala) Hydrolase Activity Alanine-tRNA Ligase Activity ATP Binding Zinc Ion Binding Amino Acid Binding Translation Regulator Activity	Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	TRNA Modification TRNA Aminoacylation For Protein Translation Alanyl-tRNA Aminoacylation TRNA Processing Cerebellar Purkinje Cell Layer Development Negative Regulation Of Neuron Apoptotic Process Neuromuscular Process Controlling Balance Mitochondrial Alanyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity Regulation Of Cytoplasmic Translational Fidelity	Translational Elongation Response To Ethanol
Pathways		Cytosolic tRNA aminoacylation	Eukaryotic Translation Elongation
Drugs		L-Alanine
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS			Body mass index ( 26426971)
Interacting Genes		1 interacting genes: EEF1B2	12 interacting genes: AARS1 APP CSNK2A1 CSNK2A2 DRD3 EEF1G HARS1 TIMP1 TPT1 ULK2 VHL WBP2
Entrez ID		16	1933
HPRD ID		03042	02804
Ensembl ID		ENSG00000090861	ENSG00000114942
Uniprot IDs		P49588	A0A024R3W7 P24534
PDB IDs		4XEM 4XEO 5KNN 5T5S 5T76 5V59	1B64 5DQS
Enriched GO Terms of Interacting Partners?
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