AK8 and HAUS1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AK8	HAUS1
Description		adenylate kinase 8	HAUS augmin like complex subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Axoneme Sperm Flagellum	Spindle Pole Centrosome Cytosol Microtubule HAUS Complex
	Molecular Function	Adenylate Kinase Activity Cytidylate Kinase Activity Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding	Molecular_function Protein Binding
	Biological Process	Nucleoside Diphosphate Phosphorylation Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Ventricular System Development Nucleoside Monophosphate Phosphorylation	G2/M Transition Of Mitotic Cell Cycle Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Spindle Assembly Cell Division Ciliary Basal Body-plasma Membrane Docking
Pathways		Interconversion of nucleotide di- and triphosphates	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs		Bis(Adenosine)-5'-Pentaphosphate
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		12 interacting genes: ALKBH3 CCDC102B FBXO7 HAUS1 MAP3K7CL MCM7 MID1IP1 PRMT6 PRRC2B RBM39 UBE2Z ZMAT2	68 interacting genes: AK8 ARFIP2 BLOC1S6 C3orf62 CAGE1 CBY2 CCDC114 CCDC136 CCDC57 CCHCR1 CDR2 CEP170P1 CEP44 CEP55 CEP57L1 CEP63 CEP70 DCTN2 DMD DTNBP1 FGFR1OP2 GOLGA2 HOOK2 IFIT3 IFT20 INCA1 KDM1A KIFC3 KRT15 KRT18 KRT19 KRT31 KRT38 KRT40 KXD1 LDOC1 LURAP1 MAD1L1 MAGEA6 MCM10 MCM3 MED4 MED7 MIPOL1 MTUS2 NDC80 NECAB2 NINL NUP54 NUP62 PDE4DIP PIBF1 SPAG5 STX11 SYCE1 SYCE3 TFIP11 TFPT TRAF1 TRIM23 TRIM27 TRIM54 TRIM69 TSG101 USHBP1 VPS52 WASHC3 ZNF471
Entrez ID		158067	115106
HPRD ID		12991	16385
Ensembl ID		ENSG00000165695	ENSG00000152240
Uniprot IDs		Q96MA6	Q96CS2
PDB IDs
Enriched GO Terms of Interacting Partners?
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