THAP6 and NUP54

		THAP6	NUP54
Description		THAP domain containing 6	nucleoporin 54
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Microtubule Cytoskeleton	Nuclear Envelope Nuclear Membrane Host Cell Nuclear Pore Central Transport Channel
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding	Protein Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Protein Targeting NLS-bearing Protein Import Into Nucleus Nuclear Pore Organization Viral Process Protein Sumoylation Viral Transcription Protein Localization To Nuclear Inner Membrane Regulation Of Protein Import Into Nucleus Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat
Pathways			ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS			Hippocampal volume ( 29274321)
Interacting Genes		3 interacting genes: KRTAP10-7 NUP54 SDCBP2	17 interacting genes: AP2B1 APC CCDC85B DGCR6 GOLIM4 HAUS1 HGS IFT20 KPNA1 KPNB1 KRT15 NR3C1 NUP62 NUTF2 SEPTIN11 SSR1 THAP6
Entrez ID		152815	53371
HPRD ID		15499	06352
Ensembl ID		ENSG00000174796	ENSG00000138750
Uniprot IDs		A0A024RDF9 Q8TBB0	Q7Z3B4
PDB IDs			4JNU 4JNV 4JO7 4JO9 5IJN 5IJO
Enriched GO Terms of Interacting Partners?
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