CTF1 and LIFR

Number of citations of the paper that reports this interaction (PubMedID 11834704)
10

Data Source:
HPRD (in vivo)

		CTF1	LIFR
Description		cardiotrophin 1	LIF receptor subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Receptor Complex Extracellular Exosome
	Molecular Function	Cytokine Activity Leukemia Inhibitory Factor Receptor Binding Protein Binding	Cytokine Receptor Activity Ciliary Neurotrophic Factor Receptor Activity Leukemia Inhibitory Factor Receptor Activity Oncostatin-M Receptor Activity Ciliary Neurotrophic Factor Receptor Binding Protein Binding Growth Factor Binding Cytokine Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Cell-cell Signaling Muscle Organ Development Positive Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway Neuron Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Neuron Development Leukemia Inhibitory Factor Signaling Pathway	Regulation Of Cytokine-mediated Signaling Pathway Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway Response To Cytokine Oncostatin-M-mediated Signaling Pathway Leukemia Inhibitory Factor Signaling Pathway Ciliary Neurotrophic Factor-mediated Signaling Pathway
Pathways		IL-6-type cytokine receptor ligand interactions	IL-6-type cytokine receptor ligand interactions RUNX1 regulates transcription of genes involved in interleukin signaling
Drugs
Diseases			Stuve-Wiedemann syndrome
GWAS		Red blood cell count ( 27863252) Triglyceride levels ( 28334899) Triglycerides ( 24097068 20686565)	Blood protein levels ( 30072576) Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Pursuit maintenance gain ( 29064472) Ulcerative colitis ( 26192919)
Interacting Genes		5 interacting genes: APP EP300 IL6ST LIFR MAGEA6	12 interacting genes: CNTF CNTFR CTF1 IL31RA IL6ST LIF MAPK1 OSM PLCG1 POU2F1 PTPN11 PTPN6
Entrez ID		1489	3977
HPRD ID		02699	01048
Ensembl ID		ENSG00000150281	ENSG00000113594
Uniprot IDs		Q16619	A8K1Z4 P42702
PDB IDs			3E0G
Enriched GO Terms of Interacting Partners?
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