SYT9 and TRPV1

Number of citations of the paper that reports this interaction (PubMedID 15066994)
100

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SYT9	TRPV1
Description		synaptotagmin 9	transient receptor potential cation channel subfamily V member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Junction Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Secretory Granule Membrane Dense Core Granule Exocytic Vesicle Hippocampal Mossy Fiber To CA3 Synapse	Cell Mitochondrion Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Cell Junction Intrinsic Component Of Plasma Membrane Dendritic Spine Membrane Neuronal Cell Body Postsynaptic Membrane
	Molecular Function	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Syntaxin Binding Clathrin Binding Identical Protein Binding	Transmembrane Signaling Receptor Activity Ion Channel Activity Extracellular Ligand-gated Ion Channel Activity Excitatory Extracellular Ligand-gated Ion Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding ATP Binding Calcium-release Channel Activity Chloride Channel Regulator Activity Phosphatidylinositol Binding Identical Protein Binding Metal Ion Binding Phosphoprotein Binding Temperature-gated Ion Channel Activity
	Biological Process	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium Ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Insulin Secretion Membrane Organization Cellular Response To Calcium Ion Calcium-dependent Activation Of Synaptic Vesicle Fusion	Negative Regulation Of Transcription By RNA Polymerase II Fever Generation Microglial Cell Activation Diet Induced Thermogenesis Peptide Secretion Negative Regulation Of Systemic Arterial Blood Pressure Lipid Metabolic Process Cell Surface Receptor Signaling Pathway Chemosensory Behavior Negative Regulation Of Heart Rate Negative Regulation Of Mitochondrial Membrane Potential Glutamate Secretion Cellular Response To Heat Positive Regulation Of Apoptotic Process Response To Peptide Hormone Positive Regulation Of Nitric Oxide Biosynthetic Process Behavioral Response To Pain Sensory Perception Of Mechanical Stimulus Thermoception Detection Of Temperature Stimulus Involved In Thermoception Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Release Of Sequestered Calcium Ion Into Cytosol Protein Homotetramerization Excitatory Postsynaptic Potential Smooth Muscle Contraction Involved In Micturition Positive Regulation Of Gastric Acid Secretion Calcium Ion Transmembrane Transport Cellular Response To Alkaloid Cellular Response To ATP Cellular Response To Tumor Necrosis Factor Cellular Response To Acidic PH Cellular Response To Temperature Stimulus Negative Regulation Of Establishment Of Blood-brain Barrier Calcium Ion Import Across Plasma Membrane Response To Capsazepine Cellular Response To Nerve Growth Factor Stimulus
Pathways		Neurexins and neuroligins Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	TRP channels
Drugs			Alpha-Linolenic Acid Icosapent Aspartame Acetaminophen Ricinoleic Acid Capsaicin Zucapsaicin
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Breast cancer and/or colorectal cancer ( 29698419) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Chagas cardiomyopathy in Tripanosoma cruzi seropositivity ( 24324551) Familial lung cancer ( 29924316) Lead levels ( 26025379) Phospholipid levels (plasma) ( 22359512) QRS duration in Tripanosoma cruzi seropositivity ( 24324551)
Interacting Genes		7 interacting genes: CSNK1A1 DNAJC5 NRXN1 SNAP25 SYNCRIP TRPV1 TUBB	8 interacting genes: AKAP5 CALM1 EGFR ITCH PRKCE SNAPIN SYT9 TRPV2
Entrez ID		143425	7442
HPRD ID		11618	03648
Ensembl ID		ENSG00000170743	ENSG00000196689
Uniprot IDs		Q86SS6	Q8NER1
PDB IDs
Enriched GO Terms of Interacting Partners?
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