CRY2 and PER3

Number of citations of the paper that reports this interaction (PubMedID 14701732)
51

Data Source:
HPRD (in vitro)

		CRY2	PER3
Description		cryptochrome circadian regulator 2	period circadian regulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytosol Nuclear Speck	Nucleus Cytoplasm
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding DNA Binding Damaged DNA Binding Single-stranded DNA Binding Deoxyribodipyrimidine Photo-lyase Activity DNA (6-4) Photolyase Activity Protein Binding Blue Light Photoreceptor Activity Phosphatase Binding FAD Binding	Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Binding Protein Binding Transcription Factor Binding Kinase Binding Ubiquitin Protein Ligase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Photoreactive Repair Circadian Rhythm Response To Light Stimulus Blue Light Signaling Pathway Response To Activity Protein-chromophore Linkage Negative Regulation Of Phosphoprotein Phosphatase Activity Circadian Regulation Of Gene Expression Glucose Homeostasis Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transcription, DNA-templated Regulation Of Sodium-dependent Phosphate Transport Negative Regulation Of Glucocorticoid Receptor Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Response To Light Stimulus Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Regulation Of Circadian Sleep/wake Cycle, Sleep Protein Stabilization
Pathways		Circadian Clock
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Axial length ( 24144296) Fasting blood glucose ( 20081858 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Glycemic traits (pleiotropy) ( 31021400) Type 2 diabetes ( 30297969) Visceral fat ( 22589738)	Chronotype ( 30696823) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600) Ulcerative colitis ( 28067908)
Interacting Genes		22 interacting genes: ATXN1 BHLHE41 BRCA1 CLOCK CTBP1 DELEC1 EZH2 LMNA MTUS2 NPAS2 PDE9A PER1 PER2 PER3 PPP2R1B PPP2R5D PPP2R5E PPP5C PTGES2 STK11 TIMELESS TTC1	9 interacting genes: ARNTL CLOCK CRY1 CRY2 CSNK1D CSNK1E PER1 PER2 SP1
Entrez ID		1408	8863
HPRD ID		07226	09138
Ensembl ID		ENSG00000121671	ENSG00000049246
Uniprot IDs		A0A0D2X7Z3 A2I2P1 Q49AN0	A0A087WV69 A2I2N5 P56645
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?