NRSN1 and SPINK1

Number of citations of the paper that reports this interaction (PubMedID 1870127)
6

Data Source:
HPRD (in vitro)

		NRSN1	SPINK1
Description		neurensin 1	serine peptidase inhibitor Kazal type 1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Transport Vesicle Growth Cone Cytoplasmic Vesicle Neuron Projection Neuronal Cell Body	Extracellular Exosome
	Molecular Function	Protein Binding	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Nervous System Development	Negative Regulation Of Nitric Oxide Mediated Signal Transduction Sperm Capacitation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Acrosome Reaction Negative Regulation Of Calcium Ion Import Negative Regulation Of Serine-type Endopeptidase Activity Regulation Of Store-operated Calcium Entry
Pathways
Drugs
Diseases			Tropical calcific pancreatitis Hereditary pancreatitis; Hereditary chronic pancreatitis
GWAS		Alzheimer's disease in hypertension ( 31055733) Information processing speed ( 21130836) Initial pursuit acceleration ( 29064472) Periodontitis (Mean PAL) ( 24024966) Squamous cell lung carcinoma ( 28604730) Type 2 diabetes ( 31049640)	Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576) Metabolite levels ( 23823483) Obesity-related traits ( 23251661)
Interacting Genes		2 interacting genes: FATE1 SPINK1	5 interacting genes: CTRC ELN NRSN1 TMPRSS15 UBE3A
Entrez ID		140767	6690
HPRD ID		18285	01341
Ensembl ID		ENSG00000152954	ENSG00000164266
Uniprot IDs		Q8IZ57	P00995
PDB IDs			1CGI 1CGJ 1HPT
Enriched GO Terms of Interacting Partners?
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