CRHR2 and UCN2

Number of citations of the paper that reports this interaction (PubMedID 11416224)
216

Data Source:
HPRD (in vitro, in vivo)

		CRHR2	UCN2
Description		corticotropin releasing hormone receptor 2	urocortin 2
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Axon Dendrite Axon Terminus	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Corticotrophin-releasing Factor Receptor Activity Peptide Hormone Binding Corticotropin-releasing Hormone Receptor Activity	Hormone Activity Hormone Binding Corticotropin-releasing Hormone Receptor Binding Corticotropin-releasing Hormone Receptor 2 Binding
	Biological Process	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Hormone-mediated Signaling Pathway Long-term Synaptic Potentiation Cellular Response To Corticotropin-releasing Hormone Stimulus	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Digestion Hormone-mediated Signaling Pathway Cellular Response To Nutrient Levels
Pathways		G alpha (s) signalling events Synthesis, secretion, and deacylation of Ghrelin ADORA2B mediated anti-inflammatory cytokines production	Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Type 2 diabetes ( 24509480 30297969)	Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Ulcerative colitis ( 28067908 25082827)
Interacting Genes		6 interacting genes: APP CRH GCC1 UCN UCN2 UCN3	2 interacting genes: CRHR2 IL10RB
Entrez ID		1395	90226
HPRD ID		03614	16171
Ensembl ID		ENSG00000106113	ENSG00000145040
Uniprot IDs		A0A090N7T4 Q13324	Q96RP3
PDB IDs		3N93 3N95 3N96	2RMG 3N95
Enriched GO Terms of Interacting Partners?
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