HDX and SUFU

  • Number of citations of the paper that reports this interaction (PubMedID 20211142)
  • 329
  • Data Source:
  • BioGRID (two hybrid)

HDX

SUFU

Description highly divergent homeobox SUFU negative regulator of hedgehog signaling
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Dentures ( 31235808)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
  • Allergy ( 27182965)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Creatinine levels ( 29403010)
  • Estimated glomerular filtration rate ( 30604766)
  • Glomerular filtration rate ( 29403010)
  • Height ( 28552196)
  • Nickel levels ( 26025379)
  • Optic disc size ( 31809533)
  • Prostate cancer ( 23535732)
  • Sum eosinophil basophil counts ( 27863252)
  • Systolic blood pressure ( 30578418)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • White blood cell count ( 29403010)
Interacting Genes 2 interacting genes: SUFU ZBTB16 27 interacting genes: BTRC FBXL17 GLI1 GLI2 GLI3 GLIS3 HDX HMGA1 HNRNPA1 ITCH LAMTOR3 LGALS3 MID1IP1 NCOA3 PEX26 PIAS1 QPRT RBPJ RCN3 RNF19A SAP18 SETDB1 STK36 ZNF219 ZNF263 ZNF446 ZNF764
Entrez ID 139324 51684
HPRD ID 06550 06124
Ensembl ID ENSG00000165259 ENSG00000107882
Uniprot IDs Q7Z353 A0A223LX15 Q9UMX1
PDB IDs 2DA4 1M1L 4BL8 4BL9 4BLA 4BLB 4BLD 4KM8 4KM9 4KMD 4KMH
Enriched GO Terms of Interacting Partners?
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