CPT1A and NPDC1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CPT1A	NPDC1
Description		carnitine palmitoyltransferase 1A	neural proliferation, differentiation and control 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Membrane Integral Component Of Mitochondrial Outer Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Carnitine O-palmitoyltransferase Activity Identical Protein Binding Palmitoleoyltransferase Activity	Protein Binding
	Biological Process	Long-chain Fatty Acid Metabolic Process Glucose Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Triglyceride Metabolic Process Carnitine Shuttle Circadian Rhythm Carnitine Metabolic Process Response To Organic Cyclic Compound Regulation Of Lipid Metabolic Process Epithelial Cell Differentiation Positive Regulation Of Fatty Acid Beta-oxidation Response To Drug Eating Behavior Regulation Of Insulin Secretion Cellular Response To Fatty Acid	Regulation Of Immune Response
Pathways		RORA activates gene expression PPARA activates gene expression Carnitine metabolism Signaling by Retinoic Acid	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		L-Carnitine Glyburide Perhexiline
Diseases		Disorders of fatty-acid oxidation, including: Medium-chain (MC) acyl-CoA dehydrogenase (AD) deficiency (MCADD); Short-chain AD deficiency (SCADD) ; Short-branched-chain AD deficiency (SBCADD) ; Very long-chain AD deficiency (VLCADD) ; Long-chain 3-hydroxyacyl CoA dehydrogenase deficiency (LCHADD) ; Trifunctional protein deficiency (TFP); Carnitine palmitoyltransferase deficiency (CPT); Carnitine-acylcarnitine translocase deficiency (CACT); Systemic primary carnitine deficiency (CDSP)
GWAS		Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Lipid metabolism phenotypes ( 22286219) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Obesity-related traits ( 23251661) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Urate levels ( 31578528)	Lymphocyte counts ( 27863252) Monocyte percentage of white cells ( 27863252) White blood cell count ( 27863252)
Interacting Genes		8 interacting genes: BCL2 CLIC1 CYBA HSPA5 KBTBD7 NPDC1 NR4A1 UBC	21 interacting genes: CCND1 CCND2 CCND3 CDK2 CPT1A E2F1 HINFP HNRNPK KHDRBS2 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-9 KRTAP4-12 KRTAP5-9 MADD MDFI NOTCH2NLA PLSCR1 TFDP1
Entrez ID		1374	56654
HPRD ID		02755	12048
Ensembl ID		ENSG00000110090	ENSG00000107281
Uniprot IDs		A0A024R5F4 B2RAQ8 P50416 Q8WZ48	Q9NQX5
PDB IDs		2LE3
Enriched GO Terms of Interacting Partners?
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