CD200R1 and CD200

Number of citations of the paper that reports this interaction (PubMedID 10981966)
119

Data Source:
HPRD (in vitro, in vivo)

		CD200R1	CD200
Description		CD200 receptor 1	CD200 molecule
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane Receptor Complex	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Axon Neuron Projection Neuronal Cell Body Cell Body
	Molecular Function	Protein Binding Immunoglobulin Receptor Activity Signaling Receptor Activity Glycosylated Region Protein Binding	Protein Binding Protein Binding Involved In Heterotypic Cell-cell Adhesion Glycosylated Region Protein Binding
	Biological Process	Signal Transduction Viral Process Heterotypic Cell-cell Adhesion Intracellular Signal Transduction Fc Receptor Signaling Pathway Regulation Of Immune Response Regulation Of Neuroinflammatory Response Negative Regulation Of Neuroinflammatory Response Negative Regulation Of Interleukin-6 Secretion Negative Regulation Of Neuron Death Negative Regulation Of Macrophage Migration Negative Regulation Of T Cell Migration	Negative Regulation Of Leukocyte Activation Negative Regulation Of Cell Proliferation Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of CREB Transcription Factor Activity Heterotypic Cell-cell Adhesion Negative Regulation Of Macrophage Activation Regulation Of Immune Response Positive Regulation Of Transforming Growth Factor Beta Production Cell-cell Adhesion Positive Regulation Of Arginase Activity Positive Regulation Of Protein-glutamine Gamma-glutamyltransferase Activity Regulation Of Neuroinflammatory Response Negative Regulation Of Neuroinflammatory Response Negative Regulation Of Interleukin-6 Secretion Negative Regulation Of Neuron Death Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Macrophage Migration Negative Regulation Of T Cell Migration
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Economic and political preferences ( 22566634) Eosinophil counts ( 27863252) Multiple sclerosis ( 31604244) Neurological blood protein biomarker levels ( 31320639) Rheumatoid arthritis ( 28118524) Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) ( 28118524) Sum eosinophil basophil counts ( 27863252)	Blood protein levels ( 30072576) Cognitive decline rate in late mild cognitive impairment ( 26252872) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		1 interacting genes: CD200	3 interacting genes: CD200R1 HCRTR2 HUS1
Entrez ID		131450	4345
HPRD ID		09609	01124
Ensembl ID		ENSG00000163606	ENSG00000091972
Uniprot IDs		Q8TD46	B4DDZ6 F8W7G1 P41217
PDB IDs
Enriched GO Terms of Interacting Partners?
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